Perspectives of using fluorescent medical technologies in inflammatory ENT-diseases diagnosis

To assess of diagnostic characteristics of fluorescent medical technologies in inflammatory ENT-diseases a technology based on the phenomenon of autofluorescence of tissue and Raman effect was used. Raman fluorescent spectroscopy is based on recording of individual molecular vibrations of unique substances in tissue. In this study we used laser radiation wavelength 532 and 405 nm for in vivo and in vitro exams. Also in the study we present spectral data obtained from palatine tonsils’ surface and pure microbial cultures in vitro. Fluorescent medical technologies help us to register and assess metabolic, morphometric and functional indices of tissue in vivo and to analyze individual spectral data of the microbial composition of the pathological focus. This study presents the experience of using such methods to evaluate the prospects of using and determining the range of clinical application of fluorescent technologies in ENT-practice.

fluorescence, sensitivity, specificity, non-invasive medical technology, express-diagnostics, Raman effect, inflammatory diseases, otorhinolaryngology

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