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Clinical importance and possibilities of laboratory diagnostics of Corynebacterium urealyticum

Abstract

In this review it has been regarded a nosocomial pathogen Corynebacterium urealyticum with respect to its laboratory investigation, relationship to diseases including cystitis, pyelonephritis, bacteremia and sepsis. It is usually missed in routine culture because of its coryneform morphology (considered as contaminant), and it requires 48 hours of incubation to grow. It can be diagnosed using phenotypic (API Coryne, urease test) and molecular methods (RT-PCR using mycobacterial primers). Recently MALDI-TOF MS has also been used for its identification. According to the information available in the literature, C. urealyticum isolates are resistent to fi-lactams, aminoglycosides, and tetracycline.

About the Authors

N. V. Evdokimova
Research Institute of Emergency Care n.a. N. V. Sklifosovsky
Russian Federation


T. V. Chernenkaya
Research Institute of Emergency Care n.a. N. V. Sklifosovsky
Russian Federation


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Review

For citations:


Evdokimova N.V., Chernenkaya T.V. Clinical importance and possibilities of laboratory diagnostics of Corynebacterium urealyticum. Medical alphabet. 2018;1(5):17-19. (In Russ.)

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