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Clinical justification of the choice of an antiseptic and an air-abrasive mixture combination in the treatment of peri-implantitis

https://doi.org/10.33667/2078-5631-2026-20-110-115

Abstract

Background. Effective decontamination of the dental implant surface, ensuring the removal of microbial biofilm while preserving the surface structure, is a key challenge in the treatment of peri-implantitis. Objective. The article deals with an evaluation of conservative peri-implantitis treatment clinical efficacy of using combinations of antiseptic solutions and air-abrasive powders. Methods. 48 patients with moderate peri-implantitis were divided into 3 groups of treatment: sodium bicarbonate and 0,01% Miramistin; erythritol and 0,05% Chlorhexidine; and glycine and Octenisept. Implant surface treatment was performed four times over a month, at 7-day intervals. Clinical efficacy was assessed using the following parameters: probing pocket depth (PPD), bleeding index (PBI), suppuration index, plaque index (PLI), gingival index (GI), and radiographic bone resorption. Examinations were conducted at baseline, and at 1 and 2.5 months. Results. All groups showed improvement in clinical and radiographic parameters. The combination of sodium bicarbonate and 0,01% Miramistin demonstrated high efficacy. At 1 month, the suppuration index was statistically significantly lower compared to the other groups, and the degree of bone resorption was also lower compared to the glycine and Octenisept group (p<0,001). By 2.5 months, bone resorption and the suppuration index were statistically significantly lower compared to the erythritol and Chlorhexidine group. The need for subsequent surgical treatment in the first group was 6,25%, which is 2 times lower than in the glycine and Octenisept group (12,5%). Conclusion. The use of an air-water abrasive mixture based on sodium bicarbonate followed by irrigation with 0,01% Miramistin provided the most pronounced reduction in clinical symptoms, stabilization of bone loss, and a decreased need for surgical treatment, which allows it to be recommended for implant surface decontamination in the treatment of peri-implantitis.

About the Authors

E. B. Strandstrem
Pirogov Russian National Research Medical University
Russian Federation

PhD applicant in Medicine of the Department of Therapeutic Dentistry.

Moscow



I. S. Kopetsky
Pirogov Russian National Research Medical University
Russian Federation

Honored Doctor of the Russian Federation, D.Sc. (Medicine), Professor, Head of the Department of Therapeutic Dentistry, Director of the Institute of Dentistry.

Moscow



A. I. Kopetskaya
Pirogov Russian National Research Medical University
Russian Federation

Assistant Professor at the Department of Therapeutic Dentistry.

Moscow



V. V. Loginov
Pirogov Russian National Research Medical University
Russian Federation

Assistant Professor at the Department of Therapeutic Dentistry.

Moscow



V. S. Kuznetsova
Central Research Institute of Dental and Maxillofacial Surgery; Research Center for Medical Genetics
Russian Federation

Cand. Sc. (Medicine), Head of the Department for Work with Grants, senior researcher at the Laboratory of Stem Cell Genetics.

Moscow



A. V. Vasiliev
Research Center for Medical Genetics; I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

D.Sc. (Medicine), Associate Professor, Professor of the Department of Surgical Dentistry, leading researcher at the Laboratory of Stem Cell Genetics.

Moscow



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Review

For citations:


Strandstrem E.B., Kopetsky I.S., Kopetskaya A.I., Loginov V.V., Kuznetsova V.S., Vasiliev A.V. Clinical justification of the choice of an antiseptic and an air-abrasive mixture combination in the treatment of peri-implantitis. Medical alphabet. 2026;(20):110-115. (In Russ.) https://doi.org/10.33667/2078-5631-2026-20-110-115

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ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)