Hereditary neuropathy with liability to pressure palsies: literature review and clinical case report
https://doi.org/10.33667/2078-5631-2026-2-37-41
Abstract
Hereditary neuropathy with a tendency to pressure palsies is a rare form of autosomal dominant hereditary peripheral neuropathy. This article reviews this disease literature. Typical changes based on family history, clinical presentation, stimulation electromyography, nerve ultrasound and genetic testing along with the disease progression and patient management strategies are presented. This article presents clinical case of hereditary neuropathy with a tendency to pressure palsies in a 21-year-old man with 9 months prospective follow-up. Nerve ultrasound, along with stimulation electromyography, has proven to be a key diagnostic method for hereditary neuropathy with a tendency to pressure palsies. The detection of two or more painless tunnel syndromes (including those detected by stimulation electromyography and ultrasound) in young patients may prompt testing for the PMP22 gene, and if detected, family genetic testing.
About the Authors
F. I. Devlikamova
Kazan State Medical Academy – branch of Russian medical Academy of continuing professional education
Russian Federation
Russian Federation
Devlikamova Farida I., Dr Med Sci (habil.), professor at Dept of Neurology
Kazan
D. R. Safina
Institute of Fundamental Medicine and Biology at Kazan Federal University
Russian Federation
Russian Federation
Safina Diana R., PhD Med Sci, associate professor at Dept of Neurology with Courses in Psychiatry, Clinical Psychology, and Medical Genetics
Kazan
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For citations:
Devlikamova F.I., Safina D.R. Hereditary neuropathy with liability to pressure palsies: literature review and clinical case report. Medical alphabet. 2026;(2):37-41. (In Russ.) https://doi.org/10.33667/2078-5631-2026-2-37-41
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