A study of the preventive properties of the innovative remineralizing gel-pencil GLOBAL WHITE

   Remineralizing therapy is in demand among the population for the prevention of caries due to the safety, simplicity, affordability, and ease of use of modern remineralizing agents. For a long time, scientists have proposed a wide variety of formulations and forms for mineralizing hard dental tissue. Currently, one of the most common options is gel formulations, which combine several mineralizing agents without interaction or mutual deactivation.A modern trend in medicine is the use of biomimetic materials. Hydroxyapatite is such a biomimetic for enamel, which has led to a large number of studies on its use.In addition to the optimal biomimetic principle of medicine, the search is ongoing for innovative remineralizing agents that are as convenient to use as possible. Therefore, the development of innovative formulations is socially in demand, especially among young people.

   Materials and methods. A comparative prospective clinical study was conducted to evaluate the remineralizing, hyposensitivity, and anti-inflammatory effects of an innovative prophylactic agent in adult patients aged 18–30 years during oral hygiene treatment compared to a control group. Standard clinical indicators were used to evaluate the effectiveness of the hygiene products: the Dental Caries Intensity Index (DMF), the Oral Hygiene Index (OHI-S), the Enamel Resistance Test (ERТ), the Gingival Inflammation Index (PMA), the Sulcus Bleeding Index (SBI), the Schiff Air Scale, and the Visual Analogue Pain Scale (VAS). Various salivary parameters were monitored during the study, including crystal formation, pH, fluoride, Ca, Mg, lactate, and IL-6. The study lasted one month.

   Results. Clinical and laboratory studies of the GLOBAL WHITE Remineralizing Gel-Pencil confirm the stated consumer properties: an increase in the level of enamel mineralization according to ERT by 36.48 %, an increase in the mineralizing potential of saliva according to microcrystallization data by 15.20 %, according to the level of salivary calcium by 20.72 %, a decrease in hyperesthesia of hard dental tissues according to the Schiff index by 45.16 %, an improvement in the condition of the periodontium during inflammation according to the PMA index by 22.48 %. The overall assessment of the organoleptic properties (including ease of application, taste, texture) was 8.86 ± 0.38 points on a 10-point scale.

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