Drug-induced bruxism. Algorithm of diagnosis and treatment
https://doi.org/10.33667/2078-5631-2025-30-54-61
Abstract
The polyetiology and diversity of manifestations of bruxism, which is accompanied by increased muscle activity, cause certain difficulties in choosing treatment methods. When analyzing recent systematic reviews of the literature on cases of drug-induced bruxism, the most common side effect in the form of jaw clenching occurred when taking selective serotonin reuptake inhibitors, especially fluoxetine, venlafaxine, and sertraline. The lack of a unified methodological approach to the diagnosis and treatment of patients with bruxism, including drug-induced bruxism, makes it difficult to plan treatment measures and prevent the development of this pathological condition. Therefore, therapy in such cases is symptomatic and aimed at preventing damage to the dental and maxillofacial system and orthopedic structures.
About the Authors
M. I. Soykher
First Moscow State Medical University I. M. Sechenov (Sechenov university)
Russian Federation
Russian Federation
Soykher Marina I.1 – Sci (habil.), Associate Professor of the Department Pediatric, Preventive Dentistry and Orthodontics
Moscow
M. G. Soykher
Kazan State Medical University of the Ministry of Health of the Russian Federation;
FSSBI «N.A. Semashko National Research Institute of Public Health»
Russian Federation
Russian Federation
Soykher Mikhail G.2, 3 – Sci (habil.), Professor of the Department Orthopedic Dentistry, Head of the Department of Dentistry
Kazan; Moscow
L. R. Mingazova
First Moscow State Medical University I. M. Sechenov (Sechenov university)
Russian Federation
Russian Federation
Mingazova Leniza R. – Sci (habil.), Professor of the Department Nervous Diseases
Moscow
D. A. Trunin
FSBEI HE SamSMU MOH
Russian Federation
Russian Federation
Trunin Dmitry A. – Sci (habil.). Professor and Head of the Department Dentistry
Samara
V. V. Govenko
FSSBI «N.A. Semashko National Research Institute of Public Health»
Russian Federation
Russian Federation
Govenko Vladimir V.3 – Graduate student Department of Dentistry
Moscow
References
1. Ebzeeva E. Yu., Polyakova O. A. «Stress and Stress-Induced Disorders» Medical Council. Vol. 16, no. 2, 2022, pp. 127–133. https://doi.org/10.21518/2079-701X-2022-16-2-127-133 2.
2. Kotova O.V., Belyaev A.A., Akarachkova E.S. Modern methods of diagnosis and treatment of anxiety and depressive disorders. RMJ. Medical Review. 2021;5(10):648–653. DOI: 10.32364/2587-6821-2021-5-10-648-653.
3. Kotsyubinskaya Yu.V. Anxiety, depression: Comorbid disorder of chronic orofacial pain in temporomandibular joint dysfunction syndrome // Review of Psychiatry and Medical Psychology named after VM Bekhterev. – 2025. https://doi.org/10.31363/2313-7053-2025-3-1061.
4. Maria Letícia de Barros Massahud, Fábio Fernandes Borém Bruzinga, Silvana Alkmim de Miranda Diniz, Karolina Kristian de Aguilar Seraidarian, Regina de Magalhães Lopes, Vinícius de Magalhães Barros, Paulo Isaias Seraidarian // Association between sleep bruxism, use of antidepressants, and obstructive sleep apnea syndrome: A cross-sectional study: Article in Journal of Oral Rehabilitation February 2022 DOI: 10.1111/joor.13312.
5. Citalopram-induced bruxism M Wise PMID: 11157444 DOI: 10.1192/bjp.178.2.182 The British Journal of Psychiatry. V. 178 , Iss. 2 , February 2001 , pp. 182 Cambridge University Press Jan 2, 2018.
6. Yevtushok V.V., Skrypnikov A.N., Boiko D.I., Sonik G.T., Borisenko V.V., Kazakov A.A. Bruxism and dental status of patients with schizophrenia under different types of drug therapy. ATJ, 2021, No 4, 116–122. DOI: 10.34921/amj.2021.4.017.
7. Falisi, G., Rastelli, C., Panti, F., Maglione, H., & Quezada Arcega, R. (2014). Psychotropic drugs and bruxism. Expert Opinion on Drug Safety, 13(10), 1319–1326. doi: 10.1517/14740338.2014.947262.
8. George, S., Joy, R., & Roy, A. (2021). Drug-Induced Bruxism: a Comprehensive Literature Review. Journal of Advanced Oral Research (1–6) 2021 Academy of Advanced Dental Research doi: 10.1177/2320206821992534.
9. Uca A., Uğuz F., Kozak H., Gümüş H., Aksoy F., Seyithanoğlu A., & Güncü Kurt H. (2015). Antidepressant-induced sleep bruxism: Prevalence, incidence, and related factors. Journal of the Neurological Sciences, 357, e96. doi: 10.1016/j.jns.2015.08.316.
10. Mingazova L.R., Orlova O.R., Soiker M.G., Soiker M.I., Artemenko A.R. Myofascial Orofacial Pain: Clinical and Pathogenetic Mechanisms, Botulinum Therapy Opportunities. Russian Journal of Pain. 2025;23(2):12–23. https://doi.org/10.17116/pain20252302112 11.
11. Clinical and economic study of the effectiveness of botulinum therapy in the relief of myogenic dental syndromes / M.I. Soikher, O.R. Orlova, M.G. Soikher, L.R. Mingazova, E. M. Soikher, D. V. Shershneva // Russian Dental Journal. – 2017. – Vol. 21, No. 6. – Pp. 308–312.
12. Bruxism and psychotropic medications. Ayman Antoun Reyad PhD, PG, Eriny Girgis BDS, MFDS, MJDF, Amin Ayoub DDS, Raafat Mishriky MBBCH, PG Dip, MRCPsych // Progress in Neurology and Psychiatry I Vol. 24 Iss. 1 2020 I (31–35).
13. Influence of selective serotonin reuptake inhibitors (SSRIs) in the development of bruxism. Article in Cranio:the Journal of Craniomandibular Practice. September 2022. doi: 10.1080/08869634.2022.2120277.
14. Guler Aksu G., & Bozduman S. (2020). Aripiprazole-induced bruxism in a child: A case report. Asia-Pacific Psychiatry. doi: 10.1111/appy.12389.
15. Drug-induced bruxism Aust Prescr 2019;42:121. https://doi.org/10.18773/austprescr.2019.048.
16. Baat C. de, Verhoeff,M., Ahlberg J., Manfredini D., Winocur E., Zweers P., Lobbezoo F. (2020). Medications and addictive substances potentially inducing or attenuating sleep bruxism and/or awake bruxism. Journal of Oral Rehabilitation. doi: 10.1111/joor.13061.
17. Mukherjee, Shatavisa & Sen, Sukanta & Biswas, Arunava & Chatterjee, Seshadri,& Tripathi, Santanu. (2014). Escitalopram Induced Bruxism: A Case Report.
Review
For citations:
Soykher M.I., Soykher M.G., Mingazova L.R., Trunin D.A., Govenko V.V. Drug-induced bruxism. Algorithm of diagnosis and treatment. Dentistry. 2025;(30):54-61. (In Russ.) https://doi.org/10.33667/2078-5631-2025-30-54-61
Views:
434
JATS XML
Email this article 