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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2025-30-54-61</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-4793</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Лекарственный бруксизм. Алгоритм диагностики и лечения</article-title><trans-title-group xml:lang="en"><trans-title>Drug-induced bruxism. Algorithm of diagnosis and treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5775-698X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сойхер</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Soykher</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сойхер Марина Ивановна – к.м.н., доцент кафедры детской, профилактической стоматологии и ортодонтии</p><p>Москва</p></bio><bio xml:lang="en"><p>Soykher Marina I.1 – Sci (habil.), Associate Professor of the Department Pediatric, Preventive Dentistry and Orthodontics</p><p>Moscow</p></bio><email xlink:type="simple">marina-soiher@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1811-3786</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сойхер</surname><given-names>М. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Soykher</surname><given-names>M. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сойхер Михаил Григорьевич– д.м.н., профессор кафедры ортопедической стоматологии, заведующей кафедрой стоматологии </p><p>Казань; Москва</p></bio><bio xml:lang="en"><p>Soykher Mikhail G.2, 3 – Sci (habil.), Professor of the Department Orthopedic Dentistry, Head of the Department of Dentistry</p><p>Kazan; Moscow</p></bio><email xlink:type="simple">msoiher@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6164-9810</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мингазова</surname><given-names>Л. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Mingazova</surname><given-names>L. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мингазова Лениза Рифкатовна – д.м.н., профессор кафедры нервных болезней ИПО</p><p>Москва</p><p> </p></bio><bio xml:lang="en"><p>Mingazova Leniza R. – Sci (habil.), Professor of the Department Nervous Diseases</p><p>Moscow</p></bio><email xlink:type="simple">msoiher@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7221-7976</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трунин</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Trunin</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трунин Дмитрий Александрович – д.м.н., профессор, заведующий кафедрой стоматологии</p><p>Самара</p></bio><bio xml:lang="en"><p>Trunin Dmitry A. – Sci (habil.). Professor and Head of the Department Dentistry </p><p>Samara</p></bio><email xlink:type="simple">trunin-027933@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-6271-9278</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Говенько</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Govenko</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Говенько Владимир Витальевич – аспирант кафедры стоматологии</p><p> </p></bio><bio xml:lang="en"><p>Govenko Vladimir V.3 – Graduate student Department of Dentistry</p><p>Moscow</p></bio><email xlink:type="simple">dr.govenko@gmail.com</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First Moscow State Medical University I. M. Sechenov (Sechenov university)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО МЗ РФ «Казанский государственный медицинский университет»; &#13;
ФГБНУ «Национальный научно-исследовательский институт общественного здоровья им. Н.А. Семашко»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan State Medical University of the Ministry of Health of the Russian Federation; &#13;
FSSBI «N.A. Semashko National Research Institute of Public Health»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО «Самарский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSBEI HE SamSMU MOH</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБНУ «Национальный научно-исследовательский институт общественного здоровья им. Н.А. Семашко»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSSBI «N.A. Semashko National Research Institute of Public Health»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>03</day><month>01</month><year>2026</year></pub-date><volume>0</volume><issue>30</issue><issue-title>Стоматология (4)</issue-title><fpage>54</fpage><lpage>61</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сойхер М.И., Сойхер М.Г., Мингазова Л.Р., Трунин Д.А., Говенько В.В., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Сойхер М.И., Сойхер М.Г., Мингазова Л.Р., Трунин Д.А., Говенько В.В.</copyright-holder><copyright-holder xml:lang="en">Soykher M.I., Soykher M.G., Mingazova L.R., Trunin D.A., Govenko V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/4793">https://www.med-alphabet.com/jour/article/view/4793</self-uri><abstract><p>Полиэтиологичность и разнообразие проявлений бруксизма, который сопровождается повышенной мышечной активностью, обуславливают определенные сложности при выборе методов лечения. При анализе последних систематических обзоров литературы о случаях возникновения лекарственного бруксизма, наиболее часто отмечают побочный эффект в виде сжатия челюстей, который возникал при приеме селективных ингибиторов обратного захвата серотонина, в особенности – флуоксетина, венлафаксина и сертралина. Отсутствие единого методического подхода к диагностике и лечению пациентов с бруксизмом, в том числе лекарственно индуцированным, затрудняет планирование лечебных мероприятий и профилактики данного патологического состояния, поэтому терапия в таких случаях является симптоматической и направлена на предотвращение повреждения органов зубочелюстной системы и ортопедических конструкций.</p></abstract><trans-abstract xml:lang="en"><p>The polyetiology and diversity of manifestations of bruxism, which is accompanied by increased muscle activity, cause certain difficulties in choosing treatment methods. When analyzing recent systematic reviews of the literature on cases of drug-induced bruxism, the most common side effect in the form of jaw clenching occurred when taking selective serotonin reuptake inhibitors, especially fluoxetine, venlafaxine, and sertraline. The lack of a unified methodological approach to the diagnosis and treatment of patients with bruxism, including drug-induced bruxism, makes it difficult to plan treatment measures and prevent the development of this pathological condition. Therefore, therapy in such cases is symptomatic and aimed at preventing damage to the dental and maxillofacial system and orthopedic structures.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>бруксизм</kwd><kwd>антидепрессанты</kwd><kwd>нейролептики</kwd><kwd>шинотерапия</kwd><kwd>стискивание и скрип зубов</kwd><kwd>гипертрофия жевательных мышц</kwd><kwd>ботулинический токсин типа А</kwd></kwd-group><kwd-group xml:lang="en"><kwd>bruxism</kwd><kwd>antidepressants</kwd><kwd>neuroleptics</kwd><kwd>splint therapy</kwd><kwd>clenching and grinding of teeth</kwd><kwd>hypertrophy of masticatory muscles</kwd><kwd>botulinum toxin type A</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Эбзеева Е. Ю., Полякова О. А. «Стресс и стресс-индуцированные расстройства» Медицинский совет. Т. 16. № 2, 2022. 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