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Methodological aspects of the informativeness of non‑commutable laboratory studies of biological analytes in the course of forensic biological examination

https://doi.org/10.33667/2078-5631-2025-22-70-73

Abstract

The article presents the results of methodological decisions for objectifying criteria for the reliability of laboratory studies of biological materials isolated from “material evidence” during forensic biological examination, i. e. not commutable for traditional laboratory technologies. The study was performed using the example of the dynamics of the content of total prostate-specific antigen in volunteers’ sperm in a laboratory model, where gauze was used as the tissue basis of “material evidence”, and the concentration of total PSA was determined by ELISA. The criteria for the reliability of laboratory test results are based on the principles of in-laboratory quality control.

About the Authors

V. L. Sidorov
St. Petersburg State Budgetary Healthcare Institution Bureau of Forensic Medical Examination; All-Russian Scientific Research and Testing Institute of Medical Technology of the Federal Service for Healthcare Supervision
Russian Federation

Sidorov Vladimir L., PhD Bio, forensic expert of the Forensic Biology Dept; research fellow at Scientific and Practical Center for Testing Medical Devices

St. Petersburg



O. D. Yagmurov
St. Petersburg State Budgetary Healthcare Institution Bureau of Forensic Medical Examination
Russian Federation

Yagmurov Orazmurad D., Dr Bio Sci (habil.), professor, head

St. Petersburg



K. T. Momynaliev
All-Russian Scientific Research and Testing Institute of Medical Technology of the Federal Service for Healthcare Supervision
Russian Federation

Momynaliev Kuvat T., Dr Bio Sci (habil.), associate professor, head of Scientific and Practical Center for Testing Medical Devices

Moscow



I. V. Birulya
Academician I. P. Pavlov First St. Petersburg State Medical University
Russian Federation

Birulya Irina V., PhD Med, associate professor at Dept of Clinical Laboratory Diagnostics with a Course in Molecular Medicine

St. Petersburg



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Review

For citations:


Sidorov V.L., Yagmurov O.D., Momynaliev K.T., Birulya I.V. Methodological aspects of the informativeness of non‑commutable laboratory studies of biological analytes in the course of forensic biological examination. Medical alphabet. 2025;(22):70-73. (In Russ.) https://doi.org/10.33667/2078-5631-2025-22-70-73

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ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)