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The effectiveness of treatment of chronic generalized periodontitis of mild severity using antimicrobial and pyle therapy

https://doi.org/10.33667/2078-5631-2025-20-87-89

Abstract

Relevance. The comparative effectiveness of antimicrobial therapy and light pyre therapy in the treatment of chronic generalized periodontitis has not been sufficiently studied. Further development and implementation of methods for the treatment of periodontal diseases with minimal drug load is necessary.

Objective. To compare the effectiveness of antimicrobial and pyler-therapy in the treatment of mild chronic generalized periodontitis.

Materials and methods. The treatment was carried out in two groups of patients (40 people each), aged from 30 to 50 years (44 women and 36 men). In the first group, Dentameth gel containing metronidazole and chlorhexidine bigluconate was used. In the second group, piper therapy was performed using the Bioptron Pro-1 device. The hygiene index and periodontal index were calculated, and the activity of neutrophilic leukocytes was determined before therapy, one, three, and six months after treatment.

Results. Antimicrobial therapy and pyler therapy have a significant positive effect on the periodontal condition of patients for three months (p<0.05). The values of the periodontal indices obtained after six months allow us to consider the treatment performed insufficient. The activity of myeloperoxidase and the number of cationic proteins intracellularly in neutrophilic leukocytes increases during the month, and decreases by three and six months, which is directly correlated with the clinical symptoms.

Conclusions. In the treatment of chronic generalized periodontitis, antimicrobial therapy and pyler-therapy show the same high efficacy, which persists for three months. When using only one of these methods as the basic active periodontal treatment, supportive periodontal therapy is indicated after three months.

About the Authors

S. N. Garazha
Federal State Budgetary Educational Institution of Higher Education «Stavropol State Medical University» of the Ministry of Healthcare of the Russian Federation
Russian Federation

Sergey N. Garazha – Grand PhD in Medical Sciences, Professor, Head of the Department of Propaedeutics of Dental Diseases

Stavropol



A. A. Dolgalev
Federal State Budgetary Educational Institution of Higher Education «Stavropol State Medical University» of the Ministry of Healthcare of the Russian Federation
Russian Federation

Alexander Alexandrovich Dolgalev – Grand PhD in Medical Sciences, Professor, Professor of the Department of General Dentistry and Pediatric Dentistry, Head of Laboratories

Stavropol



E. N. Grishilova
Federal State Budgetary Educational Institution of Higher Education «Stavropol State Medical University» of the Ministry of Healthcare of the Russian Federation
Russian Federation

Elena N. Grishilova – PhD in Medical Sciences, Associate Professor, Associate Professor of the Department of Propaedeutics of Dental Diseases

Stavropol



Z. S. Khubayev
Kadyrov Chechen State University
Russian Federation

Zelimkhan S. Khubayev – PhD in Medical Sciences, Associate Professor of the Department of General Dentistry

Grozny



L. B. Laipanova
North Caucasian State Academy
Russian Federation

Luaza B. Laipanova – PhD in Medical Sciences, Associate Professor of Orthopedic and Dental Surgery

Cherkessk



А. V. Ivashova
Federal State Budgetary Educational Institution of Higher Education «Stavropol State Medical University» of the Ministry of Healthcare of the Russian Federation
Russian Federation

Alla V. Ivashova – PhD in Medical Sciences, Associate Professor, Department of Propaedeutics of Dental Diseases

Stavropol



E. A. Belaya
Federal State Budgetary Educational Institution of Higher Education «Stavropol State Medical University» of the Ministry of Healthcare of the Russian Federation
Russian Federation

Elena A. Belaya – PhD in Medical Sciences, Associate Professor of the Department of Orthopedic Dentistry

Stavropol



D. T. Taimazova
«City dental clinic №1»
Russian Federation

Dilyara T. Taimazova – dentist-therapist

Vladikavkaz



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For citations:


Garazha S.N., Dolgalev A.A., Grishilova E.N., Khubayev Z.S., Laipanova L.B., Ivashova А.V., Belaya E.A., Taimazova D.T. The effectiveness of treatment of chronic generalized periodontitis of mild severity using antimicrobial and pyle therapy. Medical alphabet. 2025;(20):87-89. (In Russ.) https://doi.org/10.33667/2078-5631-2025-20-87-89

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ISSN 2078-5631 (Print)
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