Нативный коллаген II типа при заболеваниях опорно-двигательного аппарата: практика и перспективы применения

Коллаген – основной структурный белок соединительной ткани, составляющий более четверти всех белков организма. Из 29 известных типов коллагена особое значение имеет коллаген II типа, формирующий основу суставного хряща. В отличие от гидролизованных форм, нативный коллаген II типа (НК-II) сохраняет исходную химическую структуру, что позволяет ему выступать в качестве индуктора оральной толерантности. Клинические исследования демонстрируют эффективность НК-II в уменьшении воспаления, боли и улучшении функции суставов при остеоартрозе и ревматоидном артрите. Перспективным направлением является разработка препаратов на основе коллагена морских животных сулучшенным профилем безопасности. Необходимы масштабные исследования для оптимизации режимов испособов применения.

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