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A case of fungal mycosis in a patient with a history of superficially spreading melanoma of the skin
https://doi.org/10.33667/2078-5631-20258-96-99
Abstract
Purpose of the study. Mycosis fungoides (MF) is a tumor transformation of T-lymphocytes of the skin and belongs to cutaneous T-cell lymphomas. The etiology and pathogenesis of MF are unknown; early diagnosis based only on examination of the patient is difficult due to the variety of skin elements in MF. Cases of the development of malignant neoplasms of various localizations in patients with MF due to the developing deficiency of the T-cell component of immunity have been described. The scientific literature contains few descriptions of cases of the development of MF in patients with a history of melanoma.
Materials and methods. The presented work examines a clinical case of the development of MF in an 82-year-old woman 4 years after diagnosis and surgical treatment of superficial spreading melanoma of the skin.
Results. For the purpose of diagnosing MF and differential diagnosis with other skin pathologies, the use of immunohistochemical research is optimal.
Conclusions. The presented clinical case shows the need for long-term, possibly lifelong, observation of patients with a history of melanoma by a dermatologist, as well as the manifestation of oncological vigilance by doctors of other specialties in order to prevent the development of malignant neoplasms of the skin and other organs.
About the Authors
E. V. Okladnikova
Krasnoyarsk State Medical University named after Professor V. F. Voyno-Yasenetsky
Russian Federation
Russian Federation
Okladnikova Evgenia V., PhD Med, associate professor at Dept of Pathological Physiology named after V.V. Ivanov
Krasnoyarsk
A. R. Esimbekova
Krasnoyarsk State Medical University named after Professor V. F. Voyno-Yasenetsky
Russian Federation
Russian Federation
Esimbekova Alexandra R., assistant PhD, associate professor at Dept of Pathological Physiology named after V.V. Ivanov
Krasnoyarsk
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Review
For citations:
Okladnikova E.V., Esimbekova A.R. A case of fungal mycosis in a patient with a history of superficially spreading melanoma of the skin. Medical alphabet. 2025;(8):96-99. (In Russ.) https://doi.org/10.33667/2078-5631-20258-96-99
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