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The severity of directed tissue regeneration of connective tissue allografts and the cost-effectiveness of the resulting gum thickness in the projection of the dental implant
https://doi.org/10.33667/2078-5631-2025-10-55-62
Abstract
Currently, connective tissue autografts from the mucous membrane of the palate or from the tubercle of the upper jaw of the patient are widely used in dental implantation to increase the thickness of the gum. The main disadvantage is the presence of an additional second surgical field. Allogenic fascial limiter transplant for guided tissue regeneration «Alloplant» (Russian Federation Patent No. 2189257 A61L27/00, A01N1/00 09.20.2002; hereinafter – resorbable membrane «Alloplant») as a connective tissue allograft increases the thickness of the gum by changing the phenotype from «thin» or «medium» to «thick». This eliminates the need for a second surgical field when increasing the thickness of the gum (protected by the authors of the article by a patent of the Russian Federation) [Russian Federation, patent No. 2822326, A61C8/00, A61B17/24, 04.07.2024]. The resorbable membrane «Alloplant» is made either from the broad fascia of the thigh (FFB), from the pericardium (PC), from the dura mater (DMA). However, the manufacturer’s recommendations for the use of the fascial limiter for targeted tissue regeneration «Alloplant» do not contain information characterizing the degree of expression of targeted tissue regeneration of the resorbable membrane «Alloplant» on the gum tissue depending on the material of manufacture, namely: from FFB, from PC, from DMA. The absence of this information causes the unpredictability of the resulting gum thickness and can lead to a significant difference between the formed gum thickness and the planned one. As a result of microscopic studies of the structure of resorbable membranes «Alloplant» from SCFB, PC and TMO performed by the authors of the article, cause-andeffect relationships were revealed between the structure of the materials of the resorbable membrane «Alloplant» and the degree of its targeted effect on the regeneration of gum tissue. Recommendations for the use of resorbable membranes «Alloplant» from SCFB, PC and TMO to increase the thickness of the gum in the projection of the dental implant depending on the initial gum thickness were formulated.
About the Authors
A. A. Chekanova
Ural State Medical University
Russian Federation
Russian Federation
Anastasia A. Chekanova – PhD in Medical Sciences, Assistant at the Department of
Surgical Dentistry, Otorhinolaryngology and Maxillary Surgery,
Ekaterinburg
N. E. Selsky
Bashkir State Medical University
Russian Federation
Russian Federation
Nathan E. Selsky – Grand PhD in Medical Sciences, Professor, Professor of the Department
of Orthopedic Dentistry and Maxillofacial Surgery with IDPPO courses,
Ufa
L. A. Musina
Bashkir State Medical University
Russian Federation
Russian Federation
Lyalya A. Musina – Grand PhD in Biological Sciences, Leading Researcher of the Department of Morphology of the All-Russian Central Clinical Hospital,
Ufa
References
1. Dayronas S.K. Local anesthesia and anesthesiology in dentistry / S.K. Dayronas, E.G. Dayronas, T.V. Melenberg // A short course of lectures: a textbook. Samara, Medical University «REAVIZ», 2019 – https://reaviz.ru/sveden/files/RP_discipliny_Mestnoe_obezbolivanie_i_anesteziologiya_v_stomatologii(1).pdf.
2. Deniev A.M. Dental implantation after reconstructive surgery using revascularized autografts. Abstract: dis. for the degree of Candidate of Medical Sciences: 01/14/14 – Dentistry / Deniev Abdallah Magomedovich. – M., 2019. p. 26. https://www.dissercat.com/content/kliniko-laboratornoe-obosnovanie-novoitekhnologiivestibuloplastiki-pri-formirovanii-periim.
3. Kuri F. Regenerative methods in implantology / F. Kuri. – M.: ABC of dentists, 2013. – 678 p. https://kingmed.info/knigi/Stomatologiya/Hirurgicheskaya_stomatologiya/book_4276/Regenerativnie_metodi_v_implantologii-Kuri_F_Hanzer_T_Kuri_Ch-2013-pdf.
4. Muldashev E.R. Theoretical and applied aspects of creating allografts of the «Alloplant» series for facial plastic surgery: abstract. dis. ... Doctor of Medical Sciences // St. Petersburg, 1994, 40 p. https://www.rmj.ru/articles/obshchie-stati/Primenenie_biomateriala_Alloplant_v_hirurgii_neyrofibromatoza_ vek_1/.
5. Musienko A.I. Immediate implantation in chronic generalized periodontitis and apical granuloma. A.I. Musienko, K.I. Nesterova // Periodontology.– 2019.– N24(2).– C. 145–149. https://www.parodont.ru/jour/article/view/239?locale=ru_RU.
6. Musina L.A., Muslimov S.A., Lebedeva A.I., Volgareva E.A. Ultrastructure of macrophages detected during implantation of allogeneic biomaterial Alloplant. Morphology. – 2006. – No. 1. pp. 53–56. https://cyberleninka.ru/article/n/biomaterial-alloplant-pri-regeneratsii-miometriya-roga-matkieksperimentalnyhzhivotnyh-stimulyator-makrofagov-mezenhimnogo.
7. Musina L.A. Functional morphology of macrophages in tissue regeneration induced by allogeneic biomaterials: abstract. dis....Dr. Biol.Sciences // Saransk, 2007. – 49 p. https://www.dissercat.com/content/funktsionalnaya-morfologiya-makrofagov-pri-regeneratsii-tkanei-indutsirovannoiallogennymi-b.
8. Musina L.A., Muslimov S.A., Lebedeva A.I. Stimulation of tissue regeneration by allogeneic biomaterials. – Morphology. Saint Petersburg, Aesculapius, 2012, No. 3, pp.109–110. https://izd-mn.com/PDF/39MNNPK20.pdf.
9. Muslimov S.A. Morphological aspects of regenerative surgery // Ufa: Bashkortostan, 2000. 168 p. https://www.alloplant.ru/upload/iblock/b36/mjjq68a7r2tau4y5boyugv1uvmkrss27.pdf. Muslimov S.A. Morphological aspects of regenerative surgery // Ufa: Bashkortostan, 2000. 168 p.
10. Palacci P. Soft tissue plastic surgery in the field of implants / A. Palacci // Paradontology and restorative dentistry. – 2012. – No. 7. – pp. 161–177. https://cyberleninka.ru/article/n/profilaktika-rezorbtsii-kostnoytkani-v-periimplantatnoyzone-putem-primeneniya-soedinitelno-tkannogotransplantata-na-pitayuschey.
11. Perova M.D. Periodontal tissues: norm, pathology, ways of recovery / M.D. Perova, Moscow, 2005 – 312 p. https://www.combook.ru/product/11964785/.
12. Reshetnikov A.P., Nikityuk D.B., Urakov A.L. A method for eliminating soft tissue insufficiency around an installed implant. Application for invention RUS No. 201423087 dated 06/18/2014. https://edrid.ru/rid/216.013.6b2e.html.
13. Robert Marks. Pathology of the oral cavity and maxillofacial region in dental practice / translated by K. Gusakov, A. Ostrovsky. – 2019. https://www. dental-azbuka.ru/books/kniga_195.html.
14. Selskiy N.E., Musina L.A., Kozhemyakina E.S. A clinical and experimental study of the effectiveness of closure of mucosal perforation during sinus-lifting surgery using an allograft for targeted tissue regeneration // Ural Medical Journal, 2014, No. 7, pp. 100–103. https://cyberleninka.ru/article/n/kliniko-eksperimentalnoe-obosnovanie-effektivnosti-primeneniya-razlichnyh-tipov-materialov-pri-provedenii-operatsii-sinus-lifting/viewer.
15. Tlusenko V.P., Bayrikov I.M., Trunin D.A., Gusyakova O.A., Komlev S.S. The influence of dental prosthetics technology on the dynamics of early predictors of the inflammatory and destructive process in the periimplant zone // Bulletin of the Russian State Medical University. – 2019. № 2.https://cyberleninka.ru/article/n/vliyanietehnologii-protezirovaniyazubov-na-dinamiku-rannih-prediktorov-vospalitelnodestruktivnogo-protsessa-vperiimplantatnoy/viewer.
16. Yablokov A.E. Features of positioning dental implants / A.E. Yablokov, A.V. Ivashchenko, I.M. Fedyaev [et al.] //Medical alphabet. – 2019. – №11(2). – Pp. 33–34. https://samsmu.ru/files/referats/2020/yablokov/avtoreferat.pdf.
17. Muldashev E.R., Muslimov S.A., Musina L.A., Nigmatullin R.T., Lebedeva A.I., Shangina O.R., Khasanov R.A. et al. The role of macrophages in the tissues regeneration stimulated by the biomaterials. Cell Tissue Bank. – 2005. – Vol. 6, N 2. – P. 99–107. file:///C:/Users/chea/Downloads/eksperimentalno-mopfologicheskoe-issledovanie-vliyaniya-dispepgipovannogo-allogennogo-biomateriala-na-pegeneratsiyu-pogovitsy.pdf.
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For citations:
Chekanova A.A., Selsky N.E., Musina L.A. The severity of directed tissue regeneration of connective tissue allografts and the cost-effectiveness of the resulting gum thickness in the projection of the dental implant. Medical alphabet. 2025;(10):55-62. (In Russ.) https://doi.org/10.33667/2078-5631-2025-10-55-62
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