Connective tissue dysplasia is a basic factor for dental diseases
https://doi.org/10.33667/2078-5631-2025-10-39-42
Abstract
To date, it has been established that risk factors for the development of dental diseases are a number of general and local etiologic factors, one of which is tissue dysplasia (TD), the basis of which is hereditary collagenopathy, especially in childhood. To date, it has been established that the development of TD is influenced by aggressive factors of the external and internal environment, which affect ontogenesis and manifest themselves in characteristic external phenotypic signs of TD. In recent years, studies have appeared indicating that the state of the dental system is considered as an indicator of somatic health. The studies convincingly show that changes in the dental status of children with various health deviations are a reflection of the disorders occurring in the body. This point of view corresponds to the ideas about the unity of the structure and function of the human body systems. The morphological basis for the unity of the characteristics of dental and somatic health is the common origin of the skin, its derivatives, musculoskeletal system, facial part of the skull, heart valves, and blood vessels.
About the Authors
P. A. VoroninRussian Federation
Pavel A. Voronin – Sc. (Med), Associate Professor of the Department of Maxillofacial
Surgery and Dentistry of the Institute of Motherhood and Childhood,
Moscow
A. G. Prityko
Russian Federation
Andrey G. Prityko – Dr. Sc. (Med.), Professor, Member of the RANS, Honorary Doctor
of Russian Federation, Director, Head of the Department of Maxillofacial Surgery and
Dentistry at the Institute of Motherhood and Childhood,
Moscow
E. V. Neudakhin
Russian Federation
Evgeniy V. Neudakhin – Dr. Sc. (Med.), Professor, Honorary Doctor of Russian federation,
chiet researcher,
Moscow
V. A. Voronin
Russian Federation
Vadim A. Voronin – Sc. (Med), Associate Professor of the Department of Maxillofacial
Surgery and Dentistry of the Institute of Motherhood and Childhood,
Moscow
I. A. Nikolskaya
Russian Federation
Irina A. Nikolskaya – Candidate of Medical Sciences, Professor of the Department of Therapeutic Dentistry at the Institute of Dentistry,
Moscow
References
1. Abbakumova, V.G. Arsentiev, S.F. Gnusaev, I.I. Ivanova, T.I. Kadurina, E.L. Trisvetova, V.V. Suitcases, M.L. Chukhlovina. Multifactorial and hereditary connective tissue disorders in children. Diagnostic algorithms. Management tactics. Russian guidelines. DOI: 10.17816/PED725-39.
2. Fomina L.N. Clinical forms of connective tissue dysplasia in children / L.N. Fomina. – Petrozavodsk: Peter GU Publishing House, 2000. – 60 p.
3. Clinical recommendations of the Russian Scientific Medical Society of Internists on the diagnosis, treatment and rehabilitation of patients with connective tissue dysplasia (first revision) // Medical Bulletin of the North Caucasus. 2018. № 1.2.
4. Arsentiev V.G., Pshenichnaya KI, Suvorova A.V., Shabalov N.P. Clinical and pathogenetic aspects of disorders in the hemostasis system in connective tissue dysplasia in children // Pediatrics, 2009, vol. 88, No. 4. P. 134–140. (In Russ.)
5. Gafarov S.A., Nazarov U.K., Khen D.N., Fazilbekova G.A. General and local changes in the body, dental and immunogenetic character in undifferentiated connective tissue dysplasia. Russian Dental Journal, 2022, 26, No. 114. https//doi.org/10.17816/1728-2802-2022-261-5-14.
6. Kadurina T.I., Abakumova L.N. Assessment of the severity of undifferentiated connective tissue dysplasia in children. Moscow Bulletin of the North Caucasus. 2008. – № 2. – P. 15–21. (In Russ.)
7. Neudakhin E.V., Kozhanova T.V., Petrichenko A.V., Abramov A.A. Stress genesis of connective tissue dysplasia. Pediatrician’s practice. 2024.(2):4–13. (In Russ.)
8. Ushnitsky I.D., Nikiforova E.Yu., Cheremkina A.S., Ammosova A.M., Agafonova E.Y. Dental status of children with connective tissue dysplasia living in the Republic of Sakha. NEFU Bulletin 2015, V. 2, pp. 210–218.
9. Neudakhin E.V., Prityko A.G., Kugushev A.Yu., Meshcheryakova T.I., Suleymanov A.B. Pathogenetic features of somatic pathology in children with congenital cleft lip and palate with concomitant connective tissue dysplasia. breast cancer. Mother and child. 2021;4(4):362-369. DOI: 10.32364/2618-8430-2021-4-4-362-369.
Review
For citations:
Voronin P.A., Prityko A.G., Neudakhin E.V., Voronin V.A., Nikolskaya I.A. Connective tissue dysplasia is a basic factor for dental diseases. Medical alphabet. 2025;(10):39-42. https://doi.org/10.33667/2078-5631-2025-10-39-42
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