Analysis of the results of a microbiological study in patients with postcovid-19 necrosis of the maxillofacial region

Abstract

Postcovoid necrosis of the maxillofacial region is a severe complication of the new coronavirus infection, characterized by an inflammatory process in the paranasal sinuses in combination with necrosis of the bones of the middle zone of the face (upper jaw, nasal concha, zygomatic bone). Many studies provide information that this complication is associated with fungal lesions of the organs of the middle zone of the face with mucormycetes (mucormycosis). The article provides an analysis of the results of a microbiological study of the excretory cavity of the mouth, nasal cavity and maxillary sinus in patients with postcovoid necrosis of the maxillofacial region in comparison with patients with bisphosphonate osteonecrosis of the maxilla, chronic rhinosinusitis, as well as patients with severe COVID-19 who do not have signs of necrosis. Mucormycetes were detected only in samples from 4 patients (18%) with postcovoid necrosis of the maxillofacial region, which did not confirm the hypothesis of the predominant role of this microorganism in the pathogenesis of the complication.