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Psoriasis and oncology: is there a way out?

https://doi.org/10.33667/2078-5631-2024-25-52-57

Abstract

In severe psoriasis, systemic therapy is required, but the number of studies on the use of biologics drugs in patients with existing or history of cancer is limited, which creates difficulties in prescribing this group of drugs. The presented clinical case demonstrates the interdisciplinary interaction between a dermatologist and an oncologic surgeon. A patient diagnosed with psoriasis, psoriatic arthritis, and basal cell carcinoma underwent successful therapy with the IL-23 inhibitor risankizumab, which has demonstrated high safety and efficacy in the treatment of psoriasis, and surgical removal of the basal cell carcinoma by Mohs micrographic surgery. For patients with psoriasis and an existing or history of cancer, multidisciplinary collaboration is required to determine optimal therapeutic tactics.

About the Authors

E. A. Shatokhina
Medical Research and Educational Center of Lomonosov Moscow State University; Central State Medical Academy of the Administrative Department of the President of Russia
Russian Federation

Evgeniya A. Shatokhina - DM Sci (habil.), professor at Dept of Dermatovenereology and Cosmetology, Central State Medical Academy of the Administrative Department of the President of Russia; leading researcher at Dept of Internal Diseases, Medical Research and Educational Center of Lomonosov Moscow State University.

Moscow



D. N. Kushkin
Skin Clinic
Russian Federation

Dmitry N. Kushkin - PhD Med, chief physician.

Moscow



V. V. Andreeva
Skin Clinic; M.F. Vladimirsky Moscow Regional Research Clinical Institute
Russian Federation

Victoria V. Andreeva - DM Sci (habil.), senior researcher, M.F. Vladimirsky Moscow Regional Research Clinical Institute; plastic surgeon, maxillofacial surgeon, oncologist, Skin Clinic.

Moscow



M. A. Bobrov
Skin Clinic
Russian Federation

Maxim A. Bobrov - head of Skin Pathomorphology Laboratory, Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology; pathologist, Skin Clinic, Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology.

Moscow



A. D. Komarova
Central State Medical Academy of the Administrative Department of the President of Russia
Russian Federation

Anastasia D. Komarova - resident at Dept of Dermatovenereology and Cosmetology.

Moscow



A. S. Bridan-Rostovskaya
Central State Medical Academy of the Administrative Department of the President of Russia
Russian Federation

Anna S. Bridan-Rostovskaya - postgraduate student at Dept of Dermatovenereology and Cosmetology.

Moscow



L. S. Kruglova
Central State Medical Academy of the Administrative Department of the President of Russia
Russian Federation

Larisa S. Kruglova - DM Sci (habil.), professor, head at Dept of Dermatovenereology and Cosmetology.

Moscow



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Review

For citations:


Shatokhina E.A., Kushkin D.N., Andreeva V.V., Bobrov M.A., Komarova A.D., Bridan-Rostovskaya A.S., Kruglova L.S. Psoriasis and oncology: is there a way out? Medical alphabet. 2024;(25):52-57. (In Russ.) https://doi.org/10.33667/2078-5631-2024-25-52-57

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ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)