

Quality of life and adaptation in older men and women with chronic cerebral ischemia
https://doi.org/10.33667/2078-5631-2024-21-22-25
Abstract
Objective. To study the quality of life and adaptation of elderly men and women with chronic cerebral ischemia.
Materials and methods. The study included 65 patients (31 men and 34 women, mean age 81.6±1.1 years) diagnosed withchronic cerebral ischemia. The assessment of quality of life carried out by using the Russian version of the general questionnaire “SF-36 HEALTH STATUS SURVEY”. The level of asthenia studied using the MFI-20 questionnaire. Levels of anxiety and depression were determined using the HADS scale. Adaptive reactions studied in the leukocyte blood count by calculating the percentage of lymphocytes and segmented neutrophils.
Results. The patients rated their quality of life low in all areas, including the areas of physical capabilities, psychological well-being and social activity. A high prevalence and varying degrees of severity of asthenia, anxiety and depressive disorders revealed in all patients, more pronounced in women. The formation of homeostatic blood reactions was observed, indicating a decrease in the level of adaptation.
About the Authors
V. N. AbramovaRussian Federation
Valeria N. Abramova - PhD Med, neurologist.
Tver
T. A. Slyusar
Russian Federation
Tatyana A. Slyusar - DM Sci (habil.), professor at Dept of Neurology, Rehabilitation and Neurosurgery.
Tver
References
1. Proshchaev K.I., Ilnitsky A.N., Konovalov S.S. Selected lectures on geriatrics. Ed. corresponding member RAMN Khavinson VH. SPb.: Prime-EVROZNAK, 2008. 778 p. (In Russ.).
2. Shabalin VN. Organization of the work of geriatric services in the context of progressive demographic aging of the population of the Russian Federation. Advances in gerontology. 2009. 22; (1): 185–195. (In Russ.).
3. Kalinkin MN, Yakovlev NA, Slyusar TA. Chronic cerebral ischemia inoldage (pathogenetic and clinical aspects). Tver: RITsTSMU, 2016. 226 p. (In Russ.).
4. Gusev EI, Chukanova EI, Chukanova AS. Chronic cerebrovascular insufficiency (riskfactors, pathogenesis, clinic, treatment). M.: Act, 2018. 345 p . (In Russ.).
5. Gagliese L, Farrell MJ. Theneurobiologyofaging, nociceptionandpain: Anintegrationofanimalandhumanexperimentalevidence. In: Gibson SJ, Weiner DK, eds. Pain in Older Persons. Seattle WA: IASPPress, 2005: 25–44.
6. Burke SN, Barnes CA. Neural plasticity in the ageing brain. Nat Rev Neurosci. 2006Jan; 7(1): 30–40. Doi: 10.1038/nrn1809
7. Levin OS. Diagnosis and treatment of dementia in clinical practice. M.: MEDpres-inform, 2012. 256 p.(In Russ.).
8. Rockwood K., Wentzel S., Hachinscki V., Hogan D.B., MacKnight C., McDowell I. Prevalence and outcomes of vascular cognitive impairment. Neurology. 2000;54 (2): 447–451.
9. Kadjikov A.S., Manvelov L.S., Shahparonova N.I. Chronic vascular diseases of the brain encephalopathy. Guidefor doctors. 3rd edition, revised and expanded. M.: GEOTAR-Media, 2014. (In Russ.).
10. Putilina M. V. Asthenic disorders in general medical practice. Diagnostic and therapeutic algorithms. Nervous Diseases. 2013; 4: 26–33. (In Russ.).
11. Gusev E.I., Chukanova E.I. Modern pathogenetic aspects of chronic cerebral ischemia. Zhurnal nevrologii i psikhiatriiim. S. S. Korsakova. 2015; 115 (3): 4–8. (In Russ.).
12. Schumacher G.I. et al. Depressive disorders in patients with stage I–II discirculatory encephalopathy. SSKorsakov Journal of Neurology and Psychiatry: application «Stroke». 2007; 371–372. (In Russ.).
13. Novik A.A., Ivanova T.I. Guidelines for the study of life quality in medicine. M., 2007. 320 p. (In Russ.).
14. Stolyarenko L.D. Fundamentals of Psychology. Rostov-on-Don: Phoenix, 2002. 704 p. (In Russ.).
15. Garkavi L.Kh., Kvakina E.B., Ukolova M.A. Adaptivereactionsandbodyresistance. Rostov on Don, 1977. 273 p. (In Russ.).
16. Brazhenko N.A., Brazhenko O.N., Trofimov V.I. Adaptive reactions of the body and ways to improve the effectiveness of treatment in modern conditions. NewSt. PetersburgMedicalBulletin. 2002, 2: 49–53. (In Russ.).
17. Antiphenko E.A., Troshin V.V., Dryugina A.V. et al. Non-specific resistance of the body in chronic brain ischemia. Medicalalmanac. 2011; 1 (14): 60–62. (In Russ.).
18. Vlasova I.A. Reactions of adaptation and the functional condition of the organism of elderly persons. Sib. Med.j., 2012; 6: 46–50 (In Russ.).
19. Vein A.M., Danilov A.B. Gender problem in neurology. SS. Korsakov Journal of Neurology and Psychiatry. 2003; 10: 4–14. (In Russ.).
20. Putilina M.V. The role of endothelial dysfunction in cerebrovascular diseases. The-Doctor. 2012; 7: 24–28. (In Russ.).
21. Dyukova G.M. Depression in elderly neurological patients: diagnosis and treatment. Clinical Gerontology. 2008; 3: 67–75. (In Russ.).
22. Bendas T.V. Gender Psychology. SPb.: Peter, 2006. 431 p. (In Russ.).
23. Vorobyova P.A., Vlasova A.V. Depression in old age. Clinical Gerontology. 2007; (13) 3: 22–28. (In Russ.).
Review
For citations:
Abramova V.N., Slyusar T.A. Quality of life and adaptation in older men and women with chronic cerebral ischemia. Medical alphabet. 2024;(21):22-25. (In Russ.) https://doi.org/10.33667/2078-5631-2024-21-22-25