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Onset of Rheumatoid Arthritis with eye manifestations (clinical case report)
https://doi.org/10.33667/2078-5631-2024-10-53-56
Abstract
Objective. Rheumatoid Arthritis may onset with ocular manifestations. The purpose of our work was presentation of clinical case of the onset of rheumatoid arthritis with an eye lesion.
Materials and methods. A clinical case of rheumatoid arthritis with an atypical onset was analyzed. As well, a search and review of relevant literature was performed.
Results. Patient with rheumatoid arthritis got bilateral ulcerous keratitis, refractory to conventional treatment and complicated by bilateral corneal perforation with iris prolapse. Due to the atypical clinical course of ophthalmic lesions being insusceptible of medical treatment, the patient was examined further. Laboratory immunological workup revealed positive rheumatoid factor, anti-CCP and anti-MCV antibodies. The typical symmetric presentation of arthritis developed 8 months after the onset of ophthalmic disorders. Baseline therapy of rheumatoid arthritis has demonstrated efficacy both in controlling the joint manifestations and preventing relapse of keratitis.
Conclusion. The development of eye syndrome may precede articular manifestation of rheumatoid arthritis. While managing patients with recurrent bilateral keratitis, rheumatologic pathology should be suspected.
About the Authors
A. I. Akulova
Saratov State Medical University named after V.I. Razumovsky
Russian Federation
Russian Federation
Akulova Anna I., PhD Med, assistant at Dept of Hospital Therapy of Faculty of Medicine
Saratov
A. R. Avakian
Saratov State Medical University named after V.I. Razumovsky
Russian Federation
Russian Federation
Avakian Angelina R., 6th year student of Faculty of Medicine
Saratov
G. R. Dolishniaia
Saratov State Medical University named after V.I. Razumovsky
Russian Federation
Russian Federation
Dolishniaia Gulnara R., PhD Med, assistant at Dept of Hospital Therapy of Faculty of Medicine
Saratov
N. М. Nikitina
Saratov State Medical University named after V.I. Razumovsky
Russian Federation
Russian Federation
Nikitina Natalya M., DM Sci (habil.), head of Dept of Hospital Therapy of Faculty of Medicine
Saratov
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Review
For citations:
Akulova A.I., Avakian A.R., Dolishniaia G.R., Nikitina N.М. Onset of Rheumatoid Arthritis with eye manifestations (clinical case report). Medical alphabet. 2024;1(10):53-56. (In Russ.) https://doi.org/10.33667/2078-5631-2024-10-53-56
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