Preview

Medical alphabet

Advanced search
Open Access Open Access  Restricted Access Subscription or Fee Access

Clinical case of endometrial stromal sarcoma

https://doi.org/10.33667/2078-5631-2023-27-61-63

Abstract

Relevance. Endometrial stromal sarcomas are rare tumors that account for about 0.2% of all malignant tumors of the genital tract. It is believed that they are more common in premenopausal women. Endometrial stromal sarcomas are hormone-sensitive tumors. Because of the rarity of this tumor, there are a limited number of reports in the publications concerning the clinical control and the final result of such cases.

Purpose. To study the main pathogenetic, clinical and morphological features of endometrial stromal sarcoma on the example of a clinical case.

Materials and methods. The article presents a clinical case of malignant tumor of the uterus, histologically – endometrial stromal sarcoma.

Results and conclusions. Diagnosis of endometrial stromal sarcoma is difficult; tumor verification requires mandatory histological examination. Difficulties in diagnosis largely determine the low early detection and poor prognosis in patients with endometrial sarcomas.

About the Authors

S. S. Yashin
Samara State Medical University
Russian Federation

Yashin Sergey S., senior lecturer at Dept of General and Clinical Pathology



E. V. Luneva
Samara State Medical University
Russian Federation

Luneva Elizaveta V., student of Institute of Clinical Medicine



A. A. Goroshkina
Samara State Medical University
Russian Federation

Goroshkina Anastasia A., student of Institute of Clinical Medicine



E. P. Shatunova
Samara State Medical University
Russian Federation

Shatunova Elena P., DM Sci (habil.), professor, professor at Dept of General and Clinical Pathology



O. V. Neganova
Samara Medical University ‘REAVIZ’
Russian Federation

Neganova Olga B., PhD Med, associate professor at Dept of Obstetrics and Gynecology



O. V. Yashina
Samara City Hospital No. 10
Russian Federation

Yashina Olga V., obstetrician-gynecologist, head of Antenatal Clinic



References

1. Sofoudis C, Kalampokas T, Grigoriadis C, Kalampokas E, Bakalianou K, Salakos N. Endometrial stromal sarcoma in a 29-year-old patient. Case report and review of the literature. Eur J Gynaecol Oncol. 2012; 33 (3): 328–30.

2. Călin FD, Gheorghiu D, Ionescu CA, et al. Endometrial stromal sarcoma in a 27-year-old woman. Case report and literature review. Rom J Morphol Embryol. 2018; 59 (3): 933–938.

3. Tang Y, Chen Y, Tian L, et al. Vaginal Low-Grade Endometrial Stromal Sarcoma: An Extremely Rare Case Report and Review of the Literature. Int J Gynecol Pathol. 2020; 39 (5): 447–451. DOI: 10.1097/PGP.0000000000000626.

4. Akaev I, Yeoh CC, Rahimi S. Update on Endometrial Stromal Tumours of the Uterus. Diagnostics (Basel). 2021; 11 (3): 429. DOI: 10.3390/diagnostics11030429.

5. Yilmaz A, Rush DS, Soslow RA. Endometrial stromal sarcomas with unusual histologic features: A report of 24 primary and metastatic tumors emphasizing fibroblastic and smooth muscle differentiation. Am J Surg Pathol. 2002; 26 (9): 1142–1150. DOI: 10.1097/00000478–200209000–00004.

6. Ludovisi M, Moro F, Pasciuto T, et al. Imaging in gynecological disease (15): Clinical and ultrasound characteristics of uterine sarcoma. Ultrasound Obstet Gynecol. 2019; 54 (5): 676–687. Doi: 10.1002/uog.20270.

7. Capozzi VA, Monfardini L, Ceni V, et al. Endometrial stromal sarcoma: A review of rare mesenchymal uterine neoplasm. J Obstet Gynaecol Res. 2020; 46 (11): 2221–2236. DOI: 10.1111/jog.14436.

8. Benson C, Miah AB. Uterine sarcoma – current perspectives. Int J Women’s Health. 2017; 9: 597–606. Published 2017 Aug 31. DOI: 10.2147/ijwh.s117754.


Review

For citations:


Yashin S.S., Luneva E.V., Goroshkina A.A., Shatunova E.P., Neganova O.V., Yashina O.V. Clinical case of endometrial stromal sarcoma. Medical alphabet. 2023;(27):61-63. (In Russ.) https://doi.org/10.33667/2078-5631-2023-27-61-63

Views: 220


ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)