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Study of the antibacterial efficacy of an antiseptic drug activated by low-frequency and high-frequency ultrasound in an experiment
https://doi.org/10.33667/2078-5631-2023-20-50-55
Abstract
The aim of the work was an experimental study of the effectiveness of activation of an antiseptic drug, using low-frequency and high-frequency ultrasound, against pathogenic microorganisms obtained from periodontal pockets.
As a result of automatic cultivation of clinical strains: S. sanguis, P. intermedia, C. albicans, revealed more pronounced antimicrobial effect of Miramistin activated by low-frequency ultrasound (26.5 kHz) compared with the activation of this drug by high-frequency ultrasound (880 kHz). In the treatment of inflammatory periodontal diseases, in order to obtain a pronounced antimicrobial effect, preference should be given to the combined effects of low-frequency ultrasound and the antiseptic drug Miramistin 0.01%.
About the Authors
I. A. Paramonova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Irina A. Paramonova - Postgraduate student of the Department of Therapeutic Dentistry of the Institute of Dentistry
Moscow
A. G. Volkov
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Alexander G. Volkov - PhD, Professor of therapeutic dentistry department
Moscow
N. Zh. Dikopova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Natalya Zh. Dikopova - PhD, Associate professor
Moscow
M. S. Podporin
Federal State Budgetary Educational Institution of High Education «A.I. Yevdokimov Moscow State University of Medicine and Dentistry» of the Ministry of Healthcare
Russian Federation
Russian Federation
Mikhail S. Podporin - Ph.D., researcher, laboratory of molecular biological research
AuthorID: 819560
Moscow
Yu. O. Paramonov
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Yury O. Paramonov - PhD, Associate professor
Moscow
I. A. Nikolskaya
Pirogov Russian National Research Medical University (Pirogov Medical University)
Russian Federation
Russian Federation
Irina A. Nikolskaya - Ph.D., Associate Professor, Department of Therapeutic Dentistry, Faculty of Dentistry
Moscow
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Review
For citations:
Paramonova I.A., Volkov A.G., Dikopova N.Zh., Podporin M.S., Paramonov Yu.O., Nikolskaya I.A. Study of the antibacterial efficacy of an antiseptic drug activated by low-frequency and high-frequency ultrasound in an experiment. Medical alphabet. 2023;(20):50-55. (In Russ.) https://doi.org/10.33667/2078-5631-2023-20-50-55
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