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Potential Use of Melatonin in Periodontal Disease
https://doi.org/10.33667/2078-5631-2023-20-19-29
Abstract
Melatonin is an indoleamine that is secreted not only in the pineal gland, but also in other organs, in particular the salivary glands. Numerous studies show that melatonin levels in the saliva and serum of patients suffering from periodontal disease are reduced, suggesting that it may play an important role in protecting tissues from damage caused by oxidative stress. Melatonin helps regulate the immune response and prevents periodontal tissue damage. The inclusion of melatonin in the periodontal disease treatment regimen increases its effectiveness. Further research is needed to determine the optimal forms and dosing regimens for melatonin.
About the Authors
S. V. Orlova
Federal State Autonomous Educational Institution of Higher Education «Peoples’ Friendship University of Russia» named after Patrice Lumumba; Scientific and Practical Center for Child Psychoneurology, Moscow Department of Health
Russian Federation
Russian Federation
Orlova Svetlana Vladimirovna - Doctor of Medical Sciences, Professor, Head of the Department of Dietology and Clinical Nutrition
S. K. Zyryanov
Federal State Autonomous Educational Institution of Higher Education «Peoples’ Friendship University of Russia» named after Patrice Lumumba
Russian Federation
Russian Federation
Zyryanov Sergey Kensarinovich - MD Head of the Department of General and Clinical Pharmacology of the Medical Institute
E. A. Nikitina
Federal State Autonomous Educational Institution of Higher Education «Peoples’ Friendship University of Russia» named after Patrice Lumumba; Scientific and Practical Center for Child Psychoneurology, Moscow Department of Health
Russian Federation
Russian Federation
Nikitina Elena Alexandrovna - Ph.D., assistant professor, Department of Dietology and Clinical Nutrition
Yu. O. Tigay
Federal State Autonomous Educational Institution of Higher Education «Peoples’ Friendship University of Russia» named after Patrice Lumumba
Russian Federation
Russian Federation
Tigay Yuliya Olegovna - Assistant of the Department of Pathological Anatomy of the Medical Institute
A. A. Orlova
Federal State Autonomous Educational Institution of Higher Education «Peoples’ Friendship University of Russia» named after Patrice Lumumba
Russian Federation
Russian Federation
Orlova Anastasia Alekseevna - student of the Medical Institute
G. A. Grabovsky
Federal State Autonomous Educational Institution of Higher Education «N.I. Pirogov Russian National Research Medical University» of the Ministry of Health
Russian Federation
Russian Federation
Grabovsky Grigory Andreevich - student of the medical faculty
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Orlova S.V., Zyryanov S.K., Nikitina E.A., Tigay Yu.O., Orlova A.A., Grabovsky G.A. Potential Use of Melatonin in Periodontal Disease. Medical alphabet. 2023;(20):19-29. (In Russ.) https://doi.org/10.33667/2078-5631-2023-20-19-29
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