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Потенциальное использование мелатонина при заболеваниях пародонта
https://doi.org/10.33667/2078-5631-2023-20-19-29
Аннотация
Мелатонин представляет собой индоламин, который секретируется не только в эпифизе, но и других органах, в частности слюнных железах. Многочисленные исследования показывают, что уровень мелатонина в слюне и сыворотке пациентов, страдающих заболеваниями пародонта, снижен, что позволяет предположить, что он может играть важную роль в защите тканей от повреждений, вызванных оксидативным стрессом. Мелатонин помогает регулировать иммунный ответ и предотвращает повреждение тканей пародонта. Включение мелатонина в схему лечения заболеваний пародонта повышает ее эффективность. Необходимы дальнейшие исследования для определения оптимальных форм и режимов дозирования мелатонина.
Ключевые слова
мелатонин,
антиоксидант,
иммуномодулятор,
воспаление,
циркадность ритма,
биоритмы,
заболевания пародонта
Об авторах
С. В. Орлова
ФГАОУ ВО «Российский университет дружбы народов» имени Патриса Лумумбы; ГБУЗ Научно-практический центр детской психоневрологии департамента здравоохранения г. Москвы
Россия
Россия
Орлова Светлана Владимировна - д.м.н., проф., зав. кафедрой диетологии и клинической нутрициологии, главный научный сотрудник
С. К. Зырянов
ФГАОУ ВО «Российский университет дружбы народов» имени Патриса Лумумбы
Россия
Россия
Зырянов Сергей Кенсаринович - д.м.н., заведующий кафедрой общей и клинической фармакологи Медицинского института
Е. А. Никитина
ФГАОУ ВО «Российский университет дружбы народов» имени Патриса Лумумбы; ГБУЗ Научно-практический центр детской психоневрологии департамента здравоохранения г. Москвы
Россия
Россия
Никитина Елена Александровна - к.м.н., доцент кафедры диетологии и клинической нутрициологии, научный сотрудник
Ю. О. Тигай
ФГАОУ ВО «Российский университет дружбы народов» имени Патриса Лумумбы
Россия
Россия
Тигай Юлия Олеговна- ассистент кафедры патологической анатомии Медицинского института
А. А. Орлова
ФГАОУ ВО «Российский университет дружбы народов» имени Патриса Лумумбы
Россия
Россия
Орлова Анастасия Алексеевна - студентка Медицинского института
Г. А. Грабовский
ФГАОУ ВО «Российский Национальный Исследовательский Медицинский Университет им. Н.И. Пирогова» Министерства здравоохранения Российской Федерации
Россия
Россия
Грабовский Григорий Андреевич - студент лечебного факультета
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Рецензия
Для цитирования:
Орлова С.В., Зырянов С.К., Никитина Е.А., Тигай Ю.О., Орлова А.А., Грабовский Г.А. Потенциальное использование мелатонина при заболеваниях пародонта. Медицинский алфавит. 2023;(20):19-29. https://doi.org/10.33667/2078-5631-2023-20-19-29
For citation:
Orlova S.V., Zyryanov S.K., Nikitina E.A., Tigay Yu.O., Orlova A.A., Grabovsky G.A. Potential Use of Melatonin in Periodontal Disease. Medical alphabet. 2023;(20):19-29. (In Russ.) https://doi.org/10.33667/2078-5631-2023-20-19-29
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