Development and justification of a hardware and software complex for the diagnosis of diseases of the oral mucosa

   Relevance. Currently, a significant increase in diseases of the oral mucosa, manifested by inflammatory and destructive lesions, has been revealed. To determine the correct tactics for the treatment of inflammatory and destructive lesions in lichen planus, it is necessary to comprehensively assess the situation in the oral cavity, taking into account planimetry data, the size of the inflammatory background, the presence of exudate, the severity of pain syndrome, and also include criteria for the stages of the lesion in the evaluation system, which requires a personalized and differentiated approach to patient management tactics.

   The purpose of this work was to develop and substantiate a hardware and software complex for the diagnosis of diseases of the oral mucosa.

   Materials and methods. The study involved 34 patients with erosive and ulcerative form of lichen planus. The patients were diagnosed with pathological elements of the oral mucosa using the developed hardware and soft-ware complex. Pain was determined (in points), the area of inflammation, the area of fibrinous plaque, the total area of the lesion for 14 days. Assessment of the stages of the pathological process contributed to the differentiated appointment of pharmaceuticals. According to the results of the clinical examination, the effectiveness of the hardware and software complex for the diagnosis of diseases of the oral mucosa has been proved and justified.

   Conclusion. During the study, it was reliably proved that the use of a hardware and software complex is advisable to include in the algorithm of examination of patients with diseases of the oral mucosa. No side effects and complications were detected. When drawing up a treatment plan, it is necessary to approach each patient individually, depending on the clinical situation.

1. Gileva O. S., Feldblum I. V., Libik T. V., Baydarov A. A., Smetanin D. G., Chuprakova E. V., Sivak E. Yu., Syutkina E. S. Key dental problems of the COVID-19 pandemic period: an interdisciplinary platform. Pediatric dentistry and prevention.2021; 21 (1): 61-65. DOI: 10.33925/1683-3031-2021-21-1-61-65.

2. Ivanovsky V. A., Antonova I. N., Molokova V. A. The role of the herpes simplex virus of the first type in oral diseases in children. Pediatric dentistry and prevention. 2022. – 22 (2): 143-151. DOI: 10.33925/1683-3031-2022-22-2-143-151

3. Orekhova L. Yu., Musaeva R. C., Loboda E. S., Grinenko E. V., Gulyanov G. Yu. Assessment of hemodynamics of periodontal vessels in patients with type 1 diabetes mellitus. Periodontology. 2020; 20 (1): 9-14. doi: 10.33925/1683-3031-2020-20-1-9-14.

4. Slazhneva E. S., Tikhomirova E. A., Atrushkevich V. G. Periodontopathogens: a new view. Systematic review. Part 1. Pediatric dentistry and prevention. 2020; 20 (1): 70-76. DOI: 10.33925/1683-3031-2020-20-1-70-76.

5. Shkarin V. V., Dyachenko S. V., Makedonova Yu. A., Gavrikova L. M., Dyachenko D. Yu., Zhuravlev L. V. Evaluation of the clinical effectiveness of diagnosis and monitoring of inflammatory and destructive diseases of the oral mucosa from the perspective of a patient-oriented approach. – Endodontics Today. – 2022; 20 (1): 116-124. URL: https://elibrary.ru/item.asp?id=49065613

6. Gavrikova L. M., Makedonova Yu. A., Dyachenko S. V. Effectiveness of complex pain relief in the treatment of patients with diseases of the oral mucosa. – Russian Journal of Pain. – 2020; S: 18-19. eLibrary ID: 44008093.

7. Cerqueira J. D. M., Moura J. R., Arsati F., Lima-Arsati Y. B. O., Bittencourt R. A., Freitas V. S. Psychological disorders and oral lichen planus: A systematic review. – J Investig Clin Dent. – 2018; 9 (4): e12363. PMID: 30270524

8. Mutafchieva M. Z., Draganova-Filipova M. N., Zagorchev P. I., Tomov G. T. Oral Lichen Planus – Known and Unknown: a Review. – Folia Med (Plovdiv). – 2018; 60 (4): 528-535. PMID: 31188760

9. Parlatescu I., Tovaru M., Nicolae C. L., Sfeatcu R., Didilescu A. C. Oral health-related quality of life in different clinical forms of oral lichen planus. – Clin Oral Investig. – 2020; 24 (1): 301-308. PMID: 31098713

10. Santosh A. B. R., Muddana K. Viral infections of oral cavity. J Family Med Prim Care. 2020; 9 (1): 36-42. doi: 10.4103/jfmpc.jfmpc_807_19

11. Tampa M., Caruntu C., Mitran M., Mitran C., Sarbu I., Rusu L. C., Matei C., Constantin C., Neagu M., Georgescu S. R. Markers of Oral Lichen Planus Malignant Transformation. – Dis Markers. – 2018; 2018: 1959506. PMID: 29682099

12. Wang Y., Du G., Shi L., Shen X., Shen Z., Liu W. Altered expression of CCN1 in oral lichen planus associated with keratinocyte activation and IL-1β, ICAM1, and CCL5 up-regulation. – J Oral Pathol Med. – 2020; 49 (9): 920-925. PMID: 32740993.

13. Cassol-Spanemberg J., Rodríguez-de Rivera-Campillo M. E., Otero-Rey E. M., Estrugo-Devesa A., Jané-Salas E., López-López J. Oral lichen planus and its relationship with systemic diseases. A review of evidence. – J Clin Exp Dent. – 2018; 10 (9): e938-e944. PMID: 30386529

14. Gururaj N., Hasinidevi P., Janani V., Divynadaniel T. Diagnosis and management of oral lichen planus – Review. – J Oral Maxillofac Pathol. – 2021; 25 (3): 383-393. PMID: 35281147