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Bronchoalveolar lavage in pediatric oncohematology

https://doi.org/10.33667/2078-5631-2022-31-46-49

Abstract

Relevance. Pulmonary lesions of infectious etiology in oncohematological children are common and, in some cases, may be accompanied by a lethal outcome. When pulmonary tissue lesions on the background of hematopoiesis aplasia in the post-chemotherapy period is shown bronchoscopy to determine the genesis of the identified changes.

Aim. To determine the diagnostic value of bronchoscopy with BAL in children with oncohematological diseases.

Materials and methods. 25 bronchoscopies with BAL were performed on the basis of the endoscopic department of the Research Institute of Pediatric Oncology and Hematology.

Results. According to the results of the study in 72% of cases a microbiologic agent was detected. The most frequent pathogens obtained by the results of cultures were Haemophilus parainfluenzae, Streptococcus oralis, Neisseria macacae, Streptococcus peroris and Pseudomonas aeruginosa.

Conclusions. Bronchoscopy with BAL in children with blood system tumors is a highly informative method of pathogen detection and determination of the etiological cause of infiltrative-inflammatory changes in the lungs.

About the Authors

M. A. Krylovetskaya
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation

Krylovetskaya Maria A., Endoscopist of Endoscopy Dept

Moscow



O. A. Gusarova
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation

Gusarova Olga A., resident endoscopist at Endoscopy Dept

Moscow



R. S. Savosin
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation

Savosin Ruslan S., endoscopist of Endoscopy Dept

Moscow



T. T. Valiev
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation

Valiev Timur T., DM Sci (habil.), leading researcher, pediatric oncologist, hematologist, head of Dept of Pediatric Oncology and Hematology No. 1

Moscow



Y. P. Kuvshinov
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation

Kuvshinov Yury P., leading researcher, endoscopist, professor at Endoscopy Dept

Moscow



Z. V. Grigorievskaya
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation

Grigorievskaya Zlata V., DM Sci (habil.), bacteriologist, head of Microbiological Laboratory

Moscow



O. A. Malikhova
National Medical Research Centre of Oncology n.a. N.N. Blokhin; Russian Medical Academy for Continuing Professional Education
Russian Federation

Malikhova Olga A., DM Sci (habil.), endoscopist, head of Endoscopic Dept, professor at Dept of Oncology and Palliative Medicine

Moscow



A. O. Tumanyan
National Medical Research Centre of Oncology n.a. N.N. Blokhin
Russian Federation

Tumanyan Armen O., DM Sci (habil.), senior researcher Scientific Advisory Office

Moscow



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Review

For citations:


Krylovetskaya M.A., Gusarova O.A., Savosin R.S., Valiev T.T., Kuvshinov Y.P., Grigorievskaya Z.V., Malikhova O.A., Tumanyan A.O. Bronchoalveolar lavage in pediatric oncohematology. Medical alphabet. 2022;(31):46-49. (In Russ.) https://doi.org/10.33667/2078-5631-2022-31-46-49

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ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)