Bronchoalveolar lavage in pediatric oncohematology
https://doi.org/10.33667/2078-5631-2022-31-46-49
Abstract
Relevance. Pulmonary lesions of infectious etiology in oncohematological children are common and, in some cases, may be accompanied by a lethal outcome. When pulmonary tissue lesions on the background of hematopoiesis aplasia in the post-chemotherapy period is shown bronchoscopy to determine the genesis of the identified changes.
Aim. To determine the diagnostic value of bronchoscopy with BAL in children with oncohematological diseases.
Materials and methods. 25 bronchoscopies with BAL were performed on the basis of the endoscopic department of the Research Institute of Pediatric Oncology and Hematology.
Results. According to the results of the study in 72% of cases a microbiologic agent was detected. The most frequent pathogens obtained by the results of cultures were Haemophilus parainfluenzae, Streptococcus oralis, Neisseria macacae, Streptococcus peroris and Pseudomonas aeruginosa.
Conclusions. Bronchoscopy with BAL in children with blood system tumors is a highly informative method of pathogen detection and determination of the etiological cause of infiltrative-inflammatory changes in the lungs.
About the Authors
M. A. KrylovetskayaRussian Federation
Krylovetskaya Maria A., Endoscopist of Endoscopy Dept
Moscow
O. A. Gusarova
Russian Federation
Gusarova Olga A., resident endoscopist at Endoscopy Dept
Moscow
R. S. Savosin
Russian Federation
Savosin Ruslan S., endoscopist of Endoscopy Dept
Moscow
T. T. Valiev
Russian Federation
Valiev Timur T., DM Sci (habil.), leading researcher, pediatric oncologist, hematologist, head of Dept of Pediatric Oncology and Hematology No. 1
Moscow
Y. P. Kuvshinov
Russian Federation
Kuvshinov Yury P., leading researcher, endoscopist, professor at Endoscopy Dept
Moscow
Z. V. Grigorievskaya
Russian Federation
Grigorievskaya Zlata V., DM Sci (habil.), bacteriologist, head of Microbiological Laboratory
Moscow
O. A. Malikhova
Russian Federation
Malikhova Olga A., DM Sci (habil.), endoscopist, head of Endoscopic Dept, professor at Dept of Oncology and Palliative Medicine
Moscow
A. O. Tumanyan
Russian Federation
Tumanyan Armen O., DM Sci (habil.), senior researcher Scientific Advisory Office
Moscow
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Review
For citations:
Krylovetskaya M.A., Gusarova O.A., Savosin R.S., Valiev T.T., Kuvshinov Y.P., Grigorievskaya Z.V., Malikhova O.A., Tumanyan A.O. Bronchoalveolar lavage in pediatric oncohematology. Medical alphabet. 2022;(31):46-49. (In Russ.) https://doi.org/10.33667/2078-5631-2022-31-46-49