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Features of postcovid syndrome in patients with rheumatic diseases

https://doi.org/10.33667/2078-5631-2022-29-49-53

Abstract

Purpose of the study. To study the frequency and structure of postcovid syndrome (PCS) in patients with rheumatic diseases (RD).

Materials and methods. The study included 70 patients with RD who had a coronavirus infection during the year. A questionnaire was carried out on the severity of the coronavirus infection, persisting symptoms in the postcovid period. Questionnaires of anxiety and depression, sleep quality were used, the activity of RD was assessed.

Results. Manifestations of PCS occurred in 50 (71 %) patients, of which 47 (67 %) had 2 or more manifestations. PCS was observed equally often in patients with different severity of infection. Such the symptoms of PCS as weakness, arthralgia, increased blood pressure, shortness of breath, tachycardia prevailed during 3 months after COVID-19. Half of the patients had a decrease in the severity of weakness, arthralgia and shortness of breath after 6 months, but the destabilization of blood pressure and tachycardia remained at the same level. Such the psychoemotional manifestations of PCS as moderate depression, memory impairment, insomnia were observed.

Conclusions. More than 2/3 of patients with RS who have undergone COVID-19 are faced with PKS. In 1/3 of the examined patients with RD the duration of the persistence of symptoms of PCS exceeds 6 months after infection. After revealing of blood pressure destabilization in patients with rheumatic diseases, it is advisable to assess cardiovascular risks in patients who have undergone COVID-19.

About the Authors

N. M. Nikitina
Saratov State Medical University n. a. V.I. Razumovsky
Russian Federation

Nikitina Natalia M. - DM Sci (habil.), professor at Hospital Therapy Dept.

Saratov



N. A. Karoli
Saratov State Medical University n. a. V.I. Razumovsky
Russian Federation

Karoli Nina A. - DM Sci (habil.), professor at Hospital Therapy Dept.

Saratov



L. R. Bogdalova
Saratov State Medical University n. a. V.I. Razumovsky
Russian Federation

Bogdalova Leyla R. - assistant at Hospital Therapy Dept.

Saratov



T. V. Kanaeva
Saratov State Medical University n. a. V.I. Razumovsky
Russian Federation

Kanaeva Tatyana V. - assistant at Hospital Therapy Dept.

Saratov



N. D. Smirnova
Regional Clinical Hospital
Russian Federation

Smirnova Natalia D. - rheumatologist.

Saratov



А. P. Rebrov
Saratov State Medical University n. a. V.I. Razumovsky
Russian Federation

Rebrov Andrey P. - DM Sci (habil.), professor, head of Hospital Therapy Dept.

Saratov



References

1. Soriano J. B., Murthy S., Marshall J. C., Relan P., Diaz J. V. A clinical case definition of post COVID-19 condition by a Delphi consensus. 2021; S 1473–3099 (21) 00703–9. DOI: https://doi.org/10.1016/S1473–3099(21)00703–9

2. NICE guideline on long COVID. Previous Article Correction to Lancet Respir Med 2021; 9: 69–84. DOI: https://doi.org/10.1016/S2213–2600(21)00031-X

3. Carod-Artal FJ. Síndrome post-COVID-19: epidemiología, criterios diagnósticos y mecanismos patogénicos implicados. REV NEUROL 2021; 72: 384–396. DOI: https://doi.org/10.33588/rn.7211.2021230

4. Calabrese L, Winthrop KL. Ann Rheum Dis; 2021; 80: 679–681. DOI: https://doi.org/10.1136/annrheumdis-2021–219957

5. Lopez-Leon S, Wegman-Ostrosky T, Perelman C, Sepulveda R, Rebolledo P, Cuapio A, et al. More than 50 long-term effects of COVID-19: A systematic review and meta-analysis. Res Sq. 2021: rs.3. rs-266574. DOI: 10.21203/rs.3.rs-266574/v1.

6. Hayes LD, Ingram J and Sculthorpe NF (2021) More Than 100 Persistent Symptoms of SARS-CoV-2 (Long COVID): A Scoping Review. Front. Med. 8: 750378. DOI: 10.3389/fmed.2021.750378.

7. Baitmukhamedov Ch.T., Botabekova A. K., Dosybaeva G. N., Makhmudov Sh. A. Rheumatoid arthritis and postcovid syndrome. Scientific and Practical Rheumatology. 2022; 60 (3): 276–279. DOI: https://doi.org/10.47360/1995–4484–2022–276–279

8. Karateev A. E., Amirdzhanova V. N., Nasonov E. L., Lila A. M., Alekseeva L. I., Pogozheva E. Yu., Filatova E. S., Nesterenko V. A. Postcovid syndrome: focus on musculoskeletal pain. Scientific and practical rheumatology. 2021; 59 (3): 255–262. DOI: https://doi.org/10.47360/1995–4484–2021–255–262

9. Dennis Andrea, Wamil M, Alberts J, et al. COVERSCAN study investigators. Multiorgan impairment in low-risk individuals with post-COVID-19 syndrome: A prospective, community-based study. BMJ Open. 2021; 11 (3): e048391. DOI: 10.1136/bmjopen-2020–048391.

10. Daugherty SE, Guo Y, Heath K, et al. Risk of clinical sequelae after the acute phase of SARS-CoV-2 infection: retrospective cohort study. BMJ. 2021; 373: n1098 DOI: https://doi.org/10.1136/bmj.n1098.

11. Arutyunov G. P., Tarlovskaya E. I., Arutyunov A. G. et al. Clinical features of the post-COVID period. Results of the international registry ‘Analysis of the dynamics of comorbid diseases in patients who have undergone infection with SARSCoV-2 (ACTIVE SARS-CoV-2)’. Preliminary data (6 months of observation). Russian journal of cardiology. 2021; 26 (10): 4708. DOI: https://doi.org/10.15829/1560–4071–2021–4708

12. Petersen M. S., Kristiansen M. F., Hanusson K. D., et al. Long COVID in the Faroe Islands – a longitudinal study among non-hospitalized patients. Clin. Infect. Dis. 2021; 73 (11): e4058–e4063. DOI: https://doi.org/10.1093/cid/ciaa1792.

13. Ono K., Kishimoto M., Shimasaki T., et al. Reactive arthritis after COVID-19 infection. RMD Open. 2020; 6 (2): e001350.

14. Gasparotto M., Framba V., Piovella C., et al. Post-COVID-19 arthritis: A case report and literature review. Clin. Rheumatol. 2021; 40 (8): 3357–3362. DOI: https://doi.org/10.1007/s10067–020–05550–1

15. Hоnge B. L., Hermansen M. F., Storgaard M. Reactive arthritis after COVID-19. BMJ Case Rep. 2021; 14 (3): e241375. DOI: https://doi.org/10.1136/bcr-2020–241375

16. Roongta R., Chattopadhyay A., Ghosh A. Correspondence on ‘Onset of rheumatoid arthritis after COVID-19: coincidence or connected?’ Ann. Rheum. Dis. 2021; Ann Rheum Dis 2021. 220479. DOI: https://doi.org/10.1136/annrheumdis-2021–220479

17. Aronova E. S., Belov B. S., Gridneva G. I. Rheumatological manifestations of postcovid syndrome (literature review). Medical Alphabet. 2022; (15): 20–25. DOI: https://doi.org/10.33667/2078–5631–2022–15–20–25

18. Aronova E. S., Belov B. S., Gridneva G. I. Postcovid syndrome and rheumatic diseases: focus on rheumatoid arthritis (own data). Medical Advice. 2022; 16 (2): 108–113. DOI: https://doi.org/10.21518/2079–701X-2022–16–2–108–113

19. Оstergaard L. SARS CoV-2 related microvascular damage and symptoms during and after COVID-19: Consequences of capillary transit-time changes, tissue hypoxia and inflammation. Physiol Rep. 2021; 9 (3): e14726. DOI: https://doi.org/10.14814/phy2.14726

20. Cares-Marambio K., Montenegro-Jiménez Y., Torres-Castro R., et al. Prevalence of potential respiratory symptoms in survivors of hospital admission after coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis. Chron. Respir. Dis. 2021; 18: 14799731211002240. DOI: https://doi.org/10.1177/14799731211002240.

21. Dani M., Dirksen A., Taraborrelli P., et al. Autonomic dysfunction in ‘long COVID’: rationale, physiology and management strategies. Clin. Med. (Lond.). 2021; 21 (1): e63–e67. DOI: https://doi.org/10.7861/clinmed.2020–0896.

22. Graham E. L., Clark J. R., Orban Z. S., et al. Persistent neurologic symptoms and cognitive dysfunction in non-hospitalized Covid-19 ‘long haulers’. Ann. Clin. Transl. Neurol. 2021; 8 (5): 1073–1085. https://doi.org/10.1002/acn3.51350


Review

For citations:


Nikitina N.M., Karoli N.A., Bogdalova L.R., Kanaeva T.V., Smirnova N.D., Rebrov А.P. Features of postcovid syndrome in patients with rheumatic diseases. Medical alphabet. 2022;(29):49-53. (In Russ.) https://doi.org/10.33667/2078-5631-2022-29-49-53

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ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)