Motor cortex mapping with navigated transcranial magnetic stimulation and its clinical application
Abstract
The basics of the navigated transcranial magnetic stimulation (nTMS) and the algorithm for motor cortex mapping in particular have been described in the present article. nTMS clinical application and own experience of its use in the department of neurorehabilitation and physiotherapy of Research center of neurology have been discussed. nTMC is used for presurgical mapping in patients with brain tumors in order to determine the functional involvement of the motor cortex. Moreover, the method can be used to evaluate neuroplastic changes and prognosis in poststroke patients during motor function recovery. Finally, changes in cortical maps are characteristic of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), due to this they may shed light on the pathophysiology and be of interest for the development of diagnostic and prognostic markers in ALS.
About the Authors
A. G. Poydasheva
Research Center of Neurology
Russian Federation
Russian Federation
I. S. Bakulin
Research Center of Neurology
Russian Federation
Russian Federation
A. Yu. Chernyavskiy
Institute of Physics and Technology of Russian Academy of Science; Research Center of Neurology
Russian Federation
Russian Federation
N. A. Suponeva
Research Center of Neurology
Russian Federation
Russian Federation
M. A. Piradov
Research Center of Neurology
Russian Federation
Russian Federation
References
1. Bakulin I.S., Chervyakov A.V., Suponeva N.A. et al. Motor cortex hyperexcitability., neuroplasticity and degeneration in amyotrophic lateral sclerosis. In book: H. Foyaca-Sibat (ed.). Novel Aspects of Amyotrophic Lateral Sclerosis. InTech, 2016; 47-72.
2. Chervyakov A.V., Bakulin I.S., Savitskaya N.G. et al. Navigated transcranial magnetic stimulation in amyotrophic lateral sclerosis. // Muscle Nerve. 2015 Jan; 51(1): 125-31.
3. Julkunen P. Methods for estimating cortical motor representation size and location in navigated transcranial magnetic stimulation. // J Neurosci Methods. 2014 Jul 30; 232: 125-33.
4. Krieg S.M., Sabih J., Bulubasova L., Obermueller T., Negwer C., Janssen I., Shiban E., Meyer B., Ringel F. Preoperative motor mapping by navigated transcranial magnetic brain stimulation improves outcome for motor eloquent lesions. // Neuro Oncol. 2014 Sep; 16(9): 1274-82.
5. Lüdemann-Podubeckâ J., Nowak D.A. Mapping cortical hand motor representation using TMS: A method to assess brain plasticity and a surrogate marker for recovery of function after stroke? // Neurosci Biobehav Rev. 2016 Oct; 69: 239-51.
6. Picht T., Frey D., Thieme S., Kliesch S., Vajkoczy P. Presurgical navigated TMS motor cortex mapping improves outcome in glioblastoma surgery: a controlled observational study. // J Neurooncol. 2016 Feb; 126(3): 535-43.
7. Poydasheva A.G., Chervyakov A.V., Zmeykina E.A., Lukmanov R.H., Chernikova L.A., Suponeva N.A., Piradov M.A., Saenko I.A., Kozlovskaya I.B. Evaluation of changes in the cortical gait control in poststroke patients induced by the use of the “regent” soft exoskeleton complex (SEC) by navigated transcranial magnetic stimulation. // Human Physiology. 2016. Т. 42. № 3. С. 252-257.
8. Rossini P.M., Burke D., Chen R., Cohen L.G., Daskalakis Z., Di Iorio R., Di Lazzaro V., Ferreri F., Fitzgerald P.B., George M.S., Hallett M., Lefaucheur J.P., Langguth B., Matsumoto H., Miniussi C., Nitsche M.A., Pascual-Leone A., Paulus W., Rossi S., Rothwell J.C., Siebner H.R., Ugawa Y., Walsh V., Ziemann U2. Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee. // Clin Neurophysiol. 2015 Jun; 126(6): 1071-107.
9. Tarapore P.E., Tate M.C., Findlay A.M., Honma S.M., Mizuiri D., Berger M.S., Nagarajan S.S. Preoperative multimodal motor mapping: a comparison of magnetoencephalography imaging, navigated transcranial magnetic stimulation, and direct cortical stimulation. // J Neurosurg. 2012 Aug; 117(2): 354-62.
Review
For citations:
Poydasheva A.G., Bakulin I.S., Chernyavskiy A.Yu., Suponeva N.A., Piradov M.A. Motor cortex mapping with navigated transcranial magnetic stimulation and its clinical application. Medical alphabet. 2017;2(22):21-25. (In Russ.)
Views:
337
Email this article 