medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»medalphabet-258Research ArticleСтатьиКартирование корковых представительств мышц с помощью навигационной транскраниальной магнитной стимуляции: возможности применения в клинической практикеMotor cortex mapping with navigated transcranial magnetic stimulation and its clinical applicationПойдашеваА. Г.PoydashevaA. G.noemail@neicon.ruБакулинИ. С.BakulinI. S.noemail@neicon.ruЧернявскийА. Ю.ChernyavskiyA. Yu.noemail@neicon.ruСупоневаН. А.SuponevaN. A.noemail@neicon.ruПирадовМ. А.PiradovM. A.noemail@neicon.ruФГБНУ Научный центр неврологииРоссияResearch Center of NeurologyRussian FederationФизико-технологический институт Российской академии наук; ФГБНУ Научный центр неврологииРоссияInstitute of Physics and Technology of Russian Academy of Science; Research Center of NeurologyRussian Federation201718072017222Современная функциональная диагностика2125Copyright © Пойдашева А.Г., Бакулин И.С., Чернявский А.Ю., Супонева Н.А., Пирадов М.А., 20172017Пойдашева А.Г., Бакулин И.С., Чернявский А.Ю., Супонева Н.А., Пирадов М.А.Poydasheva A.G., Bakulin I.S., Chernyavskiy A.Y., Suponeva N.A., Piradov M.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/258

Рассмотрены основы метода навигационной транскраниальной магнитной стимуляции (нТМС), в частности, алгоритм проведения картирования корковых представительств мышц. Обсуждены возможности применения метода в клинической практике и собственный опыт использования на базе отделения нейрореабилитации и физиотерапии ФГБНУ Научный центр неврологии. нТМС используется для проведения предоперационного картирования у пациентов с опухолями головного мозга с целью определения функциональной вовлеченности двигательной коры в объемный процесс. Кроме того, метод может быть использован для оценки нейропластических изменений и прогноза восстановления в процессе постинсультной двигательной реабилитации. Наконец, изменение карт корковых представительств мыщц характерно для нейродегенеративных заболеваний, таких как боковой амиотрофический склероз (БАС) и может представлять интерес для изучения патофизиологии и разработки диагностических и прогностических маркеров заболевания.

The basics of the navigated transcranial magnetic stimulation (nTMS) and the algorithm for motor cortex mapping in particular have been described in the present article. nTMS clinical application and own experience of its use in the department of neurorehabilitation and physiotherapy of Research center of neurology have been discussed. nTMC is used for presurgical mapping in patients with brain tumors in order to determine the functional involvement of the motor cortex. Moreover, the method can be used to evaluate neuroplastic changes and prognosis in poststroke patients during motor function recovery. Finally, changes in cortical maps are characteristic of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), due to this they may shed light on the pathophysiology and be of interest for the development of diagnostic and prognostic markers in ALS.

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The authors declare that there are no conflicts of interest present.