Genetic predisposition and resistance to certain infectious diseases. IV. Tuberculosis
https://doi.org/10.33667/2078-5631-2022-6-7-10
Abstract
The review discusses issues related to genetic predisposition and resistance to tuberculosis. Genetic factors largely determine susceptibility to various diseases, including infections. The main focus is on the genes of the major histocompatibility complex and toll-like receptors. A number of genetic polymorphisms responsible for resistance and predisposition to tuberculosis and related clinical consequences are considered. Knowledge of molecular genetic biomarkers is necessary to identify risk groups and carry out predictive measures.
About the Authors
S. N. Shcherbo
Russian National Research Medical University n.a. N.I. Pirogov
Russian Federation
Russian Federation
Shcherbo Sergey N., Dr Bio Sci, prof., head of Dept of Clinical Laboratory Diagnostics
Moscow
D. S. Shcherbo
Russian National Research Medical University n.a. N.I. Pirogov
Russian Federation
Russian Federation
Scherbo Dmitry S., PhD Bio Sci, associate prof. at Dept of Clinical Laboratory Diagnostics
Moscow
N. A. Sokolova
Russian National Research Medical University n.a. N.I. Pirogov
Russian Federation
Russian Federation
Sokolova N.A., PhD Med, associate prof. at Dept of Clinical Laboratory Diagnostics
Moscow
M. I. Savina
Russian National Research Medical University n.a. N.I. Pirogov
Russian Federation
Russian Federation
Savina Marina I., Dr Bio Sci, prof., prof. at Dept of Clinical Laboratory Diagnostics
Moscow
T. I. Turkina
Russian National Research Medical University n.a. N.I. Pirogov
Russian Federation
Russian Federation
Turkina Tatiana I., Dr Bio Sci, prof., prof. at Dept of Clinical Laboratory Diagnostics
Moscow
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Review
For citations:
Shcherbo S.N., Shcherbo D.S., Sokolova N.A., Savina M.I., Turkina T.I. Genetic predisposition and resistance to certain infectious diseases. IV. Tuberculosis. Medical alphabet. 2022;1(6):7-10. (In Russ.) https://doi.org/10.33667/2078-5631-2022-6-7-10
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