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Consultation with rheumatologist: debut of systemic lupus erythematosus

https://doi.org/10.33667/2078-5631-2021-11-55-59

Abstract

Systemic lupus erythematosus (SLE) is one of the most complex rheumatological diseases, occurring with a variety of clinical forms and manifestations. The debuts and variants of the course of SLE can vary significantly, so it is called ‘chameleon disease’ or ‘the great imitator of diseases’. In 2019, a group of experts from the European Anti-Rheumatic League and the American College of Rheumatology developed the latest criteria for the diagnosis of systemic lupus erythematosus. A prerequisite for the diagnosis is a positive antinuclear factor in combination with the seven clinical criteria for SLE (constitutional, hematological, neuropsychiatric, skin‑mucosal, polyserositis, renal) and the three immunological signs (antiphospholipid antibodies, levels of complement and its fractions, SLE‑specific autoantibodies) The article describes a case of systemic lupus erythematosus, diagnosed in a patient who was admitted to the hospital with a directional diagnosis of ‘fever of unknown origin’. The diagnosis of systemic lupus erythematosus was established on the basis of seven clinical criteria and two immunological diagnostic criteria.

About the Authors

T. N. Gavva
City Clinical Hospital No. 13, Moscow
Russian Federation

Gavva Tatyana N., Phd Med, rheumatologist 

Moscow



A. A. Pecherskikh
City Clinical Hospital No. 13, Moscow
Russian Federation

Pecherskikh Andrey A., head of Therapeutic Dept 

Moscow



D. E. Gogolev
City Clinical Hospital No. 13, Moscow
Russian Federation

Gogolev Dmitry E., therapist 

Moscow



L. V. Teplova
City Clinical Hospital No. 15 n.a. O.M. Filatov
Russian Federation

Teplova Lyudmila V., PhD Med, head of Rheumatology Dept 

Moscow



Yu. S. Shklyaeva
City Clinical Hospital No. 15 n.a. O.M. Filatov
Russian Federation

Shklyaeva Yulia S., rheumatologist 

Moscow



Ya. G. Spiryakina
Russian National Research Medical University n.a. N.I. Pirogov
Russian Federation

Spiryakina Yana G., associate prof., associate prof. at Dept of Faculty Therapy 

Moscow



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Review

For citations:


Gavva T.N., Pecherskikh A.A., Gogolev D.E., Teplova L.V., Shklyaeva Yu.S., Spiryakina Ya.G. Consultation with rheumatologist: debut of systemic lupus erythematosus. Medical alphabet. 2021;1(11):55-59. (In Russ.) https://doi.org/10.33667/2078-5631-2021-11-55-59

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ISSN 2078-5631 (Print)
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