Consultation with rheumatologist: debut of systemic lupus erythematosus
https://doi.org/10.33667/2078-5631-2021-11-55-59
Abstract
Systemic lupus erythematosus (SLE) is one of the most complex rheumatological diseases, occurring with a variety of clinical forms and manifestations. The debuts and variants of the course of SLE can vary significantly, so it is called ‘chameleon disease’ or ‘the great imitator of diseases’. In 2019, a group of experts from the European Anti-Rheumatic League and the American College of Rheumatology developed the latest criteria for the diagnosis of systemic lupus erythematosus. A prerequisite for the diagnosis is a positive antinuclear factor in combination with the seven clinical criteria for SLE (constitutional, hematological, neuropsychiatric, skin‑mucosal, polyserositis, renal) and the three immunological signs (antiphospholipid antibodies, levels of complement and its fractions, SLE‑specific autoantibodies) The article describes a case of systemic lupus erythematosus, diagnosed in a patient who was admitted to the hospital with a directional diagnosis of ‘fever of unknown origin’. The diagnosis of systemic lupus erythematosus was established on the basis of seven clinical criteria and two immunological diagnostic criteria.
About the Authors
T. N. GavvaRussian Federation
Gavva Tatyana N., Phd Med, rheumatologist
Moscow
A. A. Pecherskikh
Russian Federation
Pecherskikh Andrey A., head of Therapeutic Dept
Moscow
D. E. Gogolev
Russian Federation
Gogolev Dmitry E., therapist
Moscow
L. V. Teplova
Russian Federation
Teplova Lyudmila V., PhD Med, head of Rheumatology Dept
Moscow
Yu. S. Shklyaeva
Russian Federation
Shklyaeva Yulia S., rheumatologist
Moscow
Ya. G. Spiryakina
Russian Federation
Spiryakina Yana G., associate prof., associate prof. at Dept of Faculty Therapy
Moscow
References
1. Клюквина НГ. Системная красная волчанка: многообразие форм и вариантов течения. Современная ревматология. 2011; 5 (4): 25–30. Cranberry NG. Systemic lupus erythematosus: a variety of forms and variants of the course. Modern Rheumatology. 2011; 5 (4): 25–30.
2. Насонов ЕЛ. Системная красная волчанка. Клинические рекомендации. Москва; 2010. C. 429–81. Nasonov EL. Systemic lupus erythematosus. Clinical guidelines. Moscow; 2010. P. 429–81.
3. Сторожаков Г.И., Чукаева И.И., Александров А.А. Поликлиническая терапия. Учебник. 2011. (2-е изд., перераб. и доп.). Storozhakov G.I., Chukaeva I.I., Alexandrov A.A. Outpatient therapy. Textbook. 2011. (2nd ed., Revised and enlarged).
4. M. Aringer, K. Costenbader, D. Daikh и соавт.: 2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus. Annals of Rheumatic Diseases, 2019; 78: 1151–1159.
5. Соловьев С. К., Асеева Е. А., Попкова Т. В., Лила А. М., Мазуров В. И., Насонов Е.Л. Системная красная волчанка: новые горизонты диагностики и терапии. Научно-практическая ревматология, 2020; 58 (1): 5–14. Soloviev S. K., Aseeva E. A., Popkova T. V., Leela A. M., Mazurov V. I., Nasonov E.L. Systemic lupus erythematosus: new horizons for diagnosis and therapy. Scientific and Practical Rheumatology, 2020; 58 (1): 5–14.
6. Решетняк Т.М. Лекция РМАПО, курс повышения квалификации по ревматологии 11.2020. www.youtube.com/watch?v=4JgG_A4Ut4 Reshetnyak T.M. Lecture of RMAPO, refresher course in rheumatology 11.2020. www.youtube.com/watch?v=4JgG_A4Ut4
7. Рабочая классификация клинических вариантов течения СКВ (Насонова В.А., 1972–1986). Working classification of clinical variants of the course of SLE (Nasonova V. A., 1972–1986).
8. Орлова Н.В., Чукаева И.И., Решетников И.С., Галь И.Г., Маховская Т.Г. Организационно-правовые аспекты деятельности центров здоровья. Медицинское право. 2011. № 1. С. 38–43. Orlova N.V., Chukaeva I.I., Reshetnikov I.S., Gal I.G., Makhovskaya T.G. Organizational and legal aspects of the activities of health centers. Medical Law. 2011. No. 1. P. 38–43.
9. Aikaterini Thanou, Judith A James, Cristina Arriens et al. Scoring systemic lupus erythematosus (SLE) disease activity with simple, rapid outcome measures. DOI: 10.1136/lupus-2019–000365.eCollection 2019.
10. Mosca M., Bombardieri S. Assessing remission in systemic lupus erythematosus. Clin Exp Rheumatol 2006; 24: 100–4.
11. Freire Е.А.М., Souto L.M., Ciconelli R.M. Assessment measures in systemic lupus rythematosus. Rev Bras Reumatol 2011; 51: 70–80.
12. Никифоров В.В., Колобухина Л.В., Сметанина С.В. и др. Новая коронавирусная инфекция (COVID-19): этиология, эпидемиология, клиника, диагностика, лечение и профилактика. Учебно-методическое пособие. Москва, 2020. Nikiforov V.V., Kolobukhina L.V., Smetanina S.V. and others. New coronavirus infection (COVID-19): etiology, epidemiology, clinic, diagnosis, treatment and prevention. Study Guide. Moscow, 2020.
13. Чукаева И.И., Клепикова М.В., Орлова Н.В. Выраженность маркеров воспаления у женщин с артериальной гипертонией и ожирением на фоне нарушений липидного обмена. Системные гипертензии. 2011. Т. 8. № 1. С. 48–51. Chukaeva I.I., Klepikova M.V., Orlova N.V. The severity of markers of inflammation in women with arterial hypertension and obesity on the background of lipid metabolism disorders. Systemic Hypertension. 2011. V. 8. No. 1. P. 48–51.
14. Чукаева И. И., Орлова Н. В., Хавка Н. Н. Изучение факторов воспаления у больных с метаболическим синдромом Лечебное дело. 2010. № 4. С. 50–56. Chukaeva I.I., Orlova N.V., Khavka N.N. Study of inflammation factors in patients with metabolic syndrome. Medicine. 2010. No. 4. P. 50–56.
Review
For citations:
Gavva T.N., Pecherskikh A.A., Gogolev D.E., Teplova L.V., Shklyaeva Yu.S., Spiryakina Ya.G. Consultation with rheumatologist: debut of systemic lupus erythematosus. Medical alphabet. 2021;1(11):55-59. (In Russ.) https://doi.org/10.33667/2078-5631-2021-11-55-59