Psychoemotional disorders in patients with acute and chronic leukemia

Abstract

Objective. To study the features of psychoemotional disorders and the attitude to the disease of patients with acute and chronic leukemia. Materials and methods. 40 patients with acute leukemia (AL) (24 men, 16 women, average age 34.6 ± 9.4 years), 100 patients with chronic leukemia (CHL) (59 men, 41 women; average age 67.9 ± 10.3 years) were examined. The presence and severity of asthenia were determined according to the item ‘general asthenia’ of the MFI-20 asthenia scale, insomnia – according to the criteria of the International Sleep Classification (ICDS-2). To study anxiety, C. Spielberger–Y.L. Khanin test was used, and the Zung scale was used for depression. To determine the type of attitude to the disease, the method ‘Type of attitude to the disease’ (TOBOL) was used. Results. Asthenia, reactive anxiety, and moderate depression were significantly more frequently registered in patients with OL than in patients with CHL, and sleep disorders and severe depression were recorded in patients with CHL. Correlation analysis revealed links between the level of asthenia, depression, reactive and personal anxiety in patients with AL and CHL. Patients with AL are more likely to have an adaptive attitude to the disease, compared with patients with CHL, which is associated with a shorter duration of the disease and a younger age of patients.