Up-to-date approaches to forecast of epidemiological situation with incidence of enteroviral meningitis
https://doi.org/10.33667/2078-5631-2020-18-7-12
Abstract
This work evaluates the results of long-term dynamic monitoring of non-polio enteroviruses (NPEV) circulation in the indicator subpopulation in Yekaterinburg (children aged 3 to 6 years old), isolation of this group of viruses from specimens of sewage and the spectrum of causative agents detected in the liquor of patients with enteroviral meningitis (EVM). We established a high comparability rate of Coxsackie B and ECHO virus serotypes etiologically significant in EVM and isolated from healthy carriers. NPEV detected in sewage waters over the observation period were presented mainly by Coxsackie B viruses (84.0 %), while ECHO viruses (75.6 %) dominated among the causative agents of EVM. A conclusion was made about low informative value of the sewage study results for evaluation and forecast of the EVM epidemic situation as well as about the rationale for including the screening studies of NPEV circulation in the indicator subpopulation into the system of virological and molecular genetic monitoring.
About the Authors
V. G. Akimkin
Central Research Institute of Epidemiology
Russian Federation
Moscow
Russian Federation
Moscow
I. V. Feldblum
Perm State Medical University n. a. E. A. Wagner,
Russian Federation
Perm
Russian Federation
Perm
A. V. Alimov
Yekaterinburg Research Institute of Viral Infections of the State Research Centre of Virology and Biotechnology ‘Vector’
Russian Federation
Ekaterinburg
Russian Federation
Ekaterinburg
A. G. Sergeev
Yekaterinburg Research Institute of Viral Infections of the State Research Centre of Virology and Biotechnology ‘Vector’; Ural State Medical University
Russian Federation
Ekaterinburg
Russian Federation
Ekaterinburg
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For citations:
Akimkin V.G., Feldblum I.V., Alimov A.V., Sergeev A.G. Up-to-date approaches to forecast of epidemiological situation with incidence of enteroviral meningitis. Medical alphabet. 2020;(18):7-12. (In Russ.) https://doi.org/10.33667/2078-5631-2020-18-7-12
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