Genetic predisposition and resistance to certain infectious diseases. I. AIDS
https://doi.org/10.33667/2078-5631-2019-3-22(397)-6-10
Abstract
The review addresses issues related to genetic predisposition and resistance to infectious diseases. Genetic factors largely determine the susceptibility of the body to various diseases, including infectious ones. A genetic predisposition to tuberculosis, salmonellosis, viral hepatitis, tick-borne encephalitis, Lyme disease, HIV and others is shown. Knowledge of molecular genetic biomarkers is necessary for identifying risk groups, conducting predictive measures, in particular vaccination. The main influence is given to the genes of the main histocompatibility complex; the role of mitochondrial DNA in susceptibility to HIV infection is shown.
About the Authors
S. N. Shcherbo
Russian National Research Medical University n. a. N. I. Pirogov; People’s Friendship University of Russia
Russian Federation
Russian Federation
Moscow
D. S. Shcherbo
Russian National Research Medical University n. a. N. I. Pirogov
Russian Federation
Russian Federation
Moscow
A. L. Tishchenko
People’s Friendship University of Russia
Russian Federation
Russian Federation
Moscow
M. I. Savina
Russian National Research Medical University n. a. N. I. Pirogov
Russian Federation
Russian Federation
Moscow
T. I. Turkina
Russian National Research Medical University n. a. N. I. Pirogov
Russian Federation
Russian Federation
Moscow
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Review
For citations:
Shcherbo S.N., Shcherbo D.S., Tishchenko A.L., Savina M.I., Turkina T.I. Genetic predisposition and resistance to certain infectious diseases. I. AIDS. Medical alphabet. 2019;3(22):6-10. (In Russ.) https://doi.org/10.33667/2078-5631-2019-3-22(397)-6-10
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