First experience with xenon in treatment of severe trauma in children
https://doi.org/10.33667/2078-5631-2019-2-31(406)-41-45
Abstract
Introduction. The authors discuss their first experience of applying the inert gas xenon (Xe) for relieving a persistent pain syndrome (PPS) and acute stress disorders (ASD) in children with severe injuries.
Material and methods. Seven children with severe trauma were taken into the trial: the five with severe combined trauma after a terroristic attack (Kerch, 2018) and the two with multiple dog bites. All victims had PPS and ASD after the survived fear of death. Xenon had 15–30 % concentration in oxygen . Xe-therapy lasted for 15–20 minutes.
Results. During Xe-sessions, patients were sedated. BIS-index decreased from 95.5 ± 2.5 to 86.5 ± 5.0 U (p < 0.05); mean values by Ramsay scale decreased from 5.5 ± 0.5 to 2.7 ± 1.2 scores (p < 0.05). Pain intensity by Numeric Rating Scale for Pain decreased from 4.1 ± 1.8 to 1.1 ± 0.4 scores (p < 0.05). Five sessions were needed for controlling PPS and refusing of analgesics; 12 session for phantom pains; 3 sessions for sleeplessness; 5 sessions for erasing tragic events from the memory.
Conclusion. 15–30 % Xe inhalations were effective in controlling PPS and ASD in children with severe injuries.
About the Authors
T. S. Sabinina
Scientific and Research Institute for Emergency Pediatric Surgery and Traumatology
Russian Federation
Moscow
Russian Federation
Moscow
V. G. Bagaev
Scientific and Research Institute for Emergency Pediatric Surgery and Traumatology
Russian Federation
Moscow
Russian Federation
Moscow
V. G. Amcheslavsky
Scientific and Research Institute for Emergency Pediatric Surgery and Traumatology
Russian Federation
Moscow
Russian Federation
Moscow
Yu. V. Bagaev
Scientific and Research Institute for Emergency Pediatric Surgery and Traumatology; Russian Medical Academy for Continuing Professional Education
Russian Federation
Moscow
Russian Federation
Moscow
M. V. Bykov
Scientific and Research Institute for Emergency Pediatric Surgery and Traumatology
Russian Federation
Moscow
Russian Federation
Moscow
S. N. Averyanov
Scientific and Research Institute for Emergency Pediatric Surgery and Traumatology
Russian Federation
Moscow
Russian Federation
Moscow
T. S. Novikova
Scientific and Research Institute for Emergency Pediatric Surgery and Traumatology
Russian Federation
Moscow
Russian Federation
Moscow
N. G. Raushenbakh
Scientific and Research Institute for Emergency Pediatric Surgery and Traumatology
Russian Federation
Moscow
Russian Federation
Moscow
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Review
For citations:
Sabinina T.S., Bagaev V.G., Amcheslavsky V.G., Bagaev Yu.V., Bykov M.V., Averyanov S.N., Novikova T.S., Raushenbakh N.G. First experience with xenon in treatment of severe trauma in children. Medical alphabet. 2019;2(31):41-45. (In Russ.) https://doi.org/10.33667/2078-5631-2019-2-31(406)-41-45
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