Right and left cardiac chamber measurements and pulmonary hypertension assesment in patients with pulmonary sarcohidosis by echocardiography and stress echocardiography

Sarcoidosis is a systemic disorder of unknown etiology almost universally affecting pulmonary tissue and intrathoracic lymph nodes. A. A. Wiesel (2009) and M. E. Thomeer (2005) mentioned significant differences of worldwide incidence of sarcoidosis (0.125-24.0 new cases per 100000 people per year), so annual prevalence of the disease varies from 1 to 64 cases per 100000 people per year. Such as modern diagnostic technologies became available, there are no difficulties in diagnosis of sarcoidosis of lungs and intrathoracic lymph nodes. Nevertheless cardiac involvement may be primary (due to myocardium and other heart structures infiltration by sarcoid granulomas), and secondary (due to pulmonary artery compression by intrathoracic lymph nodes and pulmonary vascular fibrosis). Most studies of heart in patients with pulmonary sarcoidosis used only rest echocardiography (Echo). Today, the in-depth cardiac examination both at rest and during exercise became available, especially to detect subclinical changes at early stages to prevent complications of the baseline disease and for prognostic objectives. Our purpose was right and left chamber quantification and pulmonary artery pressure assessment in patients with pulmonary sarcoidosis using Echo and stress-Echo. Special attention is paid to changes in global longitudinal strain and pulmonary artery systolic pressure in patients with pulmonary sarcoidosis at rest and at the peak of exercise test.

pulmonary sarcoidosis, echocardiography, stress echocardiography, ejection fraction (EF), global longitudinal strain (GLS), pulmonary hypertension (PH)

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