Sexually transmitted infections in women of reproductive age: a descriptive study
https://doi.org/10.33667/2078-5631-2026-14-23-27
Abstract
Background. The reproductive health is one of the determining factors of social well-being and public health. Sexually transmitted infections (STIs) are a common cause of various urogenital diseases. Preventive medicine, including early diagnosis of diseases, plays a significant role in maintaining reproductive health at the state level.
Objective. Assessment of the frequency of STI detection in women of reproductive age in order to form scientifically sound proposals for improving screening measures.
Materials and methods. The study includes the results of analyzes from 333482 women of reproductive age who applied to various medical organizations in the Moscow region in 2014–2023 to detect STI DNA by real-time PCR. The assessment of the age groups most susceptible to STIs was carried out using a logistic regression model.
Results. Chlamydia trachomatis DNA was detected in 1.8 % of samples, Neisseria gonorrhoeae – 0.2 %, Mycoplasma genitalium – 0.7 %, Trichomonas vaginalis – 0.4 %. A statistically significant increase in the chance of developing C. trachomatis was shown in women aged 18–29 years, N. gonorrhoeae and M. genitalium aged 18–25 years, T. vaginalis at 38–45 years (p < 0,005).
Conclusion. STIs are important factors influencing the development of diseases of the genitourinary system. In the Moscow region, DNA of STI pathogens was found in 2.9 % of women 18–45 years old. The age risk groups for C. trachomatis are 18–29 years old, N. gonorrhoeae and M. genitalium are 18–25 years old, and T. vaginalis is 38–45 years old. A systematic approach to the diagnosis and treatment of STIs will reduce the incidence of STIs, complications of the genitourinary system and improve reproductive health.
About the Authors
T. I. MakhovaRussian Federation
Tamara I. Makhova, PhD Med Sci, senior researcher
Laboratory of Molecular Diagnostics and Epidemiology of Reproductive Organ Infections
Moscow
M. A. Vinokurov
Russian Federation
Michail A. Vinocurov, PhD Med Sci
Laboratory of Molecular Methods for Genetic Polymorphisms Research
Moscow
T. S. Skachkova
Russian Federation
Tatyana S. Skachkova, PhD Med Sci, acting head of Laboratory
Laboratory of Molecular Diagnostics and Epidemiology of Reproductive Organ Infections
Moscow
A. V. Gromova
Russian Federation
Anastasia V. Gromova, PhD Vet Sci, senior researcher
Laboratory of Molecular Diagnostics and Epidemiology of Reproductive Organ Infections
Moscow
M. A. Kaspirovich
Russian Federation
Marina A. Kaspirovich, cosmetologist
Moscow
V. G. Akimkin
Russian Federation
Vasily G. Akimkin, RAS academician, Dr Med Sci (habil.), professor, director
Moscow
References
1. Cherkassky B. L. Handbook of General Epidemiology. Moscow, 2001. 560 p. (In Russ.).
2. Clinical guidelines. «Gonococcal infection». 2024. (In Russ.).
3. Clinical guidelines. «Urogenital diseases caused by Mycoplasma genitalium». 2024. (In Russ.).
4. Clinical guidelines. «Urogenital trichomoniasis». 2024. (In Russ.).
5. Clinical guidelines. «Chlamydial infection». 2024. (In Russ.).
6. Workowski KA. Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines. Clin Infect Dis. 2015 Dec 15; 61 Suppl 8: S 759–62. DOI: 10.1093/cid/civ771
7. White J. A., Dukers-Muijrers N.H., Hoebe C. J., Kenyon C. R., Dc Ross J., Unemo M. 2025 European guideline on the management of Chlamydia trachomatis infections. Int J STD AIDS. 2025 May; 36 (6): 434–449. DOI: 10.1177/09564624251323678. Epub 2025 Mar 4. PMID: 40037375.
8. Unemo M., Ross J., Serwin A. B., Gomberg M., Cusini M., Jensen J. S. 2020 European guideline for the diagnosis and treatment of gonorrhoea in adults. Int J STD AIDS. 2020 Oct 29: 956462420949126. DOI: 10.1177/0956462420949126. Epub ahead of print. PMID: 33121366.
9. Jensen J. S., Cusini M., Gomberg M., Moi H., Wilson J., Unemo M. 2021 European guideline on the management of Mycoplasma genitalium infections. J Eur Acad Dermatol Venereol. 2022 May; 36 (5): 641–650. DOI: 10.1111/jdv.17972. Epub 2022 Feb 19. PMID: 35182080.
10. Sherrard J., Wilson J., Donders G., Mendling W., Jensen J. S. 2023 update to 2018 European (IUSTI/WHO) guideline on the management of vaginal discharge. Int J STD AIDS. 2023 Sep; 34 (10): 745. DOI: 10.1177/09564624231179277. Epub 2023 Jun 6. PMID: 37279873.
11. UK Health Security Agency Guidance NCSP: programme overview. URL: https://www.gov.uk/government/publications/ncsp-programme-overview/ncsp-programme-overview
12. Sharypova S. Yu. Behavioral factors of reproductive health in Russians. Zdorov’e Naseleniya i Sreda Obitaniya. 2024; 32 (11): 24–31. (In Russ.) DOI: 10.35627/2219-5238/2024-32-11-24-31
13. World Health Organization. Sexually transmitted infections (STIs). URL: https://www.who.int/ru/news-room/fact-sheets/detail/sexually-transmitted-infections-(stis)
14. Centers for Disease Control and Prevention. Atlas Plus STD. URL: https://gis.cdc.gov/grasp/nchhstpatlas/tables.html
15. Public Health Agency of Canada. Reported cases from 1924 to 2021 in Canada – Notifiable diseases on-line. URL: https://www.gov.uk/government/statistics/sexually-transmitted-infections-stis-annual-data-tables
16. Decision of the Council on Regional Healthcare under the Federation Council on the topic «Reproductive health of the population: a modern approach to preservation, diagnosis and treatment as a factor in improving the demographic situation in the country» (February 19, 2025). URL: http://council.gov.ru/structure/docs/88005/ (In Russ.).
17. Petrova D., Garcia-Retamero R. Effective Evidence-Based Programs for Preventing Sexually-Transmitted Infections: A Meta-Analysis. Curr HIV Res. 2015;13 (5): 432–8. DOI: 10.2174/1570162x13666150511143943
18. Jamison C. D., Coleman J. S., Mmeje O. Improving Women's Health and Combatting Sexually Transmitted Infections Through Expedited Partner Therapy. Obstet Gynecol. 2019 Mar; 133 (3): 416–422. DOI: 10.1097/AOG.0000000000003088
Review
For citations:
Makhova T.I., Vinokurov M.A., Skachkova T.S., Gromova A.V., Kaspirovich M.A., Akimkin V.G. Sexually transmitted infections in women of reproductive age: a descriptive study. Medical alphabet. 2026;(14):23-27. (In Russ.) https://doi.org/10.33667/2078-5631-2026-14-23-27
JATS XML
























