

Analysis of the relationship between lung cancer incidence rates and components polluting atmospheric air in the Khanty-Mansi autonomous okrug – Yugra
https://doi.org/10.33667/2078-5631-2024-17-27-32
Abstract
Over the 20 years of the study period in Ugra there has been an increase in the standardized lung cancer incidence rate for 20 years of the study period in Ugra there is an increase in the standardized lung cancer incidence rate. The risk of lung cancer development is closely related to environmental factors, the main of which are: tobacco smoking and air pollution with carcinogens. We studied average annual concentrations of atmospheric air pollutants and standardized incidence rates of lung cancer in men and women in the territories of the county. As a result of cross-correlation analysis it was obtained that delayed correlation of lung cancer morbidity and average annual concentrations of formaldehyde in atmospheric air in men and women is manifested after 10–16 years of exposure; phenol after 13–17 years after exposure; nitrogen dioxide after 14–15 years after exposure
About the Authors
A. A. MordovskyRussian Federation
Mordovsky Alexey A. - oncologist
Author ID: 1095026
Surgut
A. M. Parsadanyan
Russian Federation
Parsadanyan Ararat M. - DM Sci (habil.), professor at Dept of Surgical Diseases; oncologist
Author ID: 404711
Surgut
A. A. Aksarin
Russian Federation
Aksarin Alexey A. - DM Sci (habil.), head of District Oncology Center
Author ID: 256495
Surgut
P. P. Troyan
Russian Federation
Troyan Pavel P. - head of Dept of Clinical Diagnostic Oncology Center
Author ID: 1045697
Surgut
A. I. Pakhtusov
Russian Federation
Pakhtusov Alexey I. - 2nd year graduate student
Author ID: 1210401
Surgut
Yu. S. Kirillova
Russian Federation
Kirillova Yulia S. - environmental engineer
Surgut
References
1. GLOBOCAN 2020: estimated cancer incidence, mortality and prevalence worldwide in 2020 [Electronic resource]. International Agency for Research on Cancer, World Health Organization. 2018. URL: http://globocan.iarc.fr/
2. The state of oncological care for the population of Russia in 2021. Ed. Kaprina A.D., Starinsky V. V., Petrova G.V. Moscow: Moscow Research Institute of Oncology n.a. P.A. Herzen –a branch of the Federal State Budgetary Institution National Medical Research Center for Radiology, 2021. 239 p.
3. Goldstraw P. et al. The IASLC lung cancer staging project: proposals for revision of the TNM stage groupings in the forthcoming (eighth) edition of the TNM classification for lung cancer. Journal of Thoracic Oncology. 2016; 11 (1): 39–51. https://doi.org/10.1016/j.jtho.2015.09.009
4. Mordovsky A.A., Aksarin A.A., Parsadanyan A.M., Ter Ovanesov M.D., Troyan P.P. Lung cancer incidence and mortality in the Khanty-Mansi autonomous okrug – Yugra. Siberian Journal of Oncology. 2021; 20 (4): 30–38. https://doi.org/10.21294/1814–4861–2021–20–4–30–38
5. Condition of oncological care of the population of Khanty-Mansiysk Autonomous Okrug-Ugra in 2020. Khanty-Mansiysk, 2021. 118 p..
6. Zaridze D.G. Prevention of malignant neoplasms / D.G. Zaridze, D.M. Maksimovich. Success of molecular oncology. 2017; 4 (2): 8–25. https://doi.org/10.17650/2313–805X-2017–4–2–8–25
7. Mikhailov E.A. et al. Study of smoking anamnesis in patients with malignant neoplasms. Bulletin Russian Cancer Research Center named after N.N. Blokhin Russian Academy of Medical Science. 2009; 20 (1): 36–42.
8. WHO Global Report on Trends in Prevalence of Tobacco Smoking 2000–2025, second edition / World Health Organization: Geneva. Switzerland, 2018. P. 1–120.
9. Zheng М. Classification and Pathology of Lung Cancer / M. Zheng. Surg. Oncol. Clin. N. Am. 2016; 25 (3): 447–468. http://dx.doi.org/10.1016/j.soc.2016.02.003
10. Field R.W. Occupational and environmental causes of lung cancer / R.W. Field, B. L. Withers. Clinics in chest medicine. 2012; 33 (4): 681–703. https://doi.org/10.1016/j.ccm.2012.07.001
11. Rushton L. The burden of occupational cancer in Great Britain / L. Rushton, S. Bagga, R. Bevan. Published by the Health and Safety, 2012. 94 p. https://doi.org/10.1038/bjc.2012.112
12. Yarmoshenko I.V., Malinovsky G.P., Vasiliev A.V. Generalization of oncological studies of the relationship of lung cancer with radon // Labor medicine and industrial ecology. 2019; 59 (2): 92–96. https://doi.org/10.31089/1026–9428–2019–2–92–96
13. Mukheria A. F., Zaridze D.G. Epidemiology and prevention of lung cancer. Bulletin Russian Cancer Research Center named after N.N. Blokhin Russian Academy of Medical Science. 2010; 21 (3): 3–13.
14. Sorahan T. Cancer risks in a historical UK cohort of benzene exposed workers / T. Sorahan, L. J. Kinlen, R. Doll. Occupational and Environmental Medicine. 2005; 62 (4): 231–236. https://doi.org/10.1136/oem.2004.015628
15. Bessonova T.N. Assessment of technogenic impact on the atmosphere of the Khanty-Mansiysk Autonomous Okrug-Ugra / T.N. Bessonova, A.R. Groshev. Economic Bulletin of RGU. 2008; 6 (4–2): 305–308.
16. Bazhin N.M. Methane in the Environment. Ecology. Series of analytical reviews of the world literature. 2010; 93: 1–56.
17. Red Book of Khanty-Mansiysk Autonomous Okrug-Ugra: Animals, plants, mushrooms. Izd. 2 / under. ed. A.M. Vasin, A. L. Vasina. Yekaterinburg: Basco Publishing House, 2013. 460 p.
18. Coggon D. et al. Extended follow-up of a cohort of British chemical workers exposed to formaldehyde. Journal of the National Cancer Institute. 2003; 95 (21): 1608–1615. https://doi.org/10.1093/jnci/djg046
19. Luo J. et al. Association between six environmental chemicals and lung cancer incidence in the United States. Journal of environmental and public health.– 2011. https://doi.org/10.1155/2011/463701
20. Sperelakis N. (ed.). Cell physiology sourcebook: a molecular approach. Elsevier, 2001.
21. Belitsky G.A. et al. Chemical carcinogenesis and primary prevention of cancer. M.: Publishing house «ABV-press», 2020. 492 p.
22. Ashrafian L.A, Kiselev V.I, Kuznetsov I.N, Muizhnek EL, Gerfanova E.V, Vashakmadze S. L. Molecular cancer biology and prospects for effective therapy. P.A. Herzen Journal of Oncology. 2016; 5 (3): 80–87. https://doi.org/10.17116/onkolog20165280–87
23. Gantsev Sh. Kh. Oncology: Textbook for students of medical universities. 2nd edition, revised and supplemented. М.: LLC «Medical Information Agency. 2006. P. 18–38
24. Trapeznikov N.N., Shain A.A. Oncology: textbook. Medicine, 1992.
25. Petrova G. V., Gretsova O. P., Caprin A. D., Vinsky V.V. Characteristics and methods of calculation of medical-statistical indicators used in oncology. Moscow, 2014. 40 p.
26. Glanz S. Biomedical statistics: translation. with. eng. / S. Glanz. M. Practice, 1999. 459 p.
27. Rosenberg G.S. Ecological forecasting (functional predictors of time series) / G.S. Rosenberg, V.K. Shitikov, G.N. Brusilovsky; Russian Academy of Sciences; Institute of Ecology of the Volga basin RAS. Tolyatti: Institute of Ecology of the Volga Basin RAS, 1994. 182 p. EDN ZUMJSP
Review
For citations:
Mordovsky A.A., Parsadanyan A.M., Aksarin A.A., Troyan P.P., Pakhtusov A.I., Kirillova Yu.S. Analysis of the relationship between lung cancer incidence rates and components polluting atmospheric air in the Khanty-Mansi autonomous okrug – Yugra. Medical alphabet. 2024;(17):27-32. (In Russ.) https://doi.org/10.33667/2078-5631-2024-17-27-32