

Benign paroxysmal positional vertigo: case developed with hyperparathyreoidism and vitamin D deficiency
https://doi.org/10.33667/2078-5631-2024-2-50-52
Abstract
The most common cause of spinning vertigo is benign paroxysmal positional vertigo (BPPV). Most cases are related to idiopathic BPPV, which pathogenesis is still not fully understood. In this manuscript the clinical case of recurrent benign paroxysmal positional vertigo is depicted. BPPV in this case was occurred primary in menopausal period. A clinical feature of this case is its combination not only with vitamin D deficiency and postmenopausal osteopenia (confirmed according to osteodensitometry), but also with secondary hyperparathyroidism, laboratory confirmed. The literature has accumulated data to link the development and recurrence of BPPV with vitamin D deficiency and osteoporosis, but few comprehensive studies of all crucial indicators of calcium-phosphorus metabolism in these patients have been published. Meanwhile, according to the author, a comprehensive endocrinological study of calcium-phosphorus metabolism in a patient with newly diagnosed BPPV can help optimize therapy for this category of patients.
About the Author
A. S. BedenkoRussian Federation
Bedenko Anna S. - PhD Med, neurologist.
Moscow
References
1. Bronshtein AM, Lempert T. Dizziness. Moscow: GEOTAR-Media; 2019. 216 s. (In Russ.)
2. Bedenko AS, Antonenko LM, Barinov AN. Metabolic Disorders in the Pathogenesis of Various Causes of Dizziness and Instability. Annals of the Russian Academy of Medical Sciences. 2020;75(6):605–608. (in Russ)] doi: https://doi.org/10.15690/vramn1244.
3. He L. L., Li X. Y., Hou M. M., Li X. Q. Association between bone mineral density and benign paroxysmal positional vertigo: a meta-analysis. Eur Arch Otorhinolaryngol. 2019 Jun;276 (6):1561–1571. doi: 10.1007/s00405–019–05345–4.
4. Vibert D., Kompis M., Häusler R. Benign paroxysmal positional vertigo in older women may be related to osteoporosis and osteopenia. Ann Otol Rhi-nol Laryngol. 2003.112 (10): 885–889.
5. Chen J., Zhang S., Cui K., Liu C. Risk factors for benign paroxysmal positional vertigo recurrence: a systematic review and meta-analysis. J Neurol. 2021 Nov; 268(11): 4117–4127. doi: 10.1007/s00415–020–10175–0. Epub 2020 Aug 24. PMID: 32839838.
6. AlGarni M.A., Mirza A. A., Althobaiti A. A., Al-Nemari H.H., Bakhsh L. S. Association of benign paroxysmal positional vertigo with vitamin D deficiency: a systematic review and meta-analysis. Eur Arch Otorhinolaryngol. 2018 Nov;275(11):2705–2711. doi: 10.1007/s00405–018–5146–6. Epub 2018 Oct 9. PMID: 30302575.
7. Kahraman S. S., Ozcan O., Arlietal C. Calcium Homeostasis During Attack and Remission in Patients With Idiopathic Benign Paroxysmal Positional Vertigo. Otol Neurotol. 2016. 37(9): 1388–1392. doi: 10.1097/MAO.0000000000001167.
8. Kazantsev AIu, Iakupov E. Z. Evaluation of the vitamin D deficiency study in patients with benign paroxysmal positional vertigo: a retrospective clinical study. Farmateka. 2020;3(27):89–95 (in Russian).] DOI:10.18565/pharmateca.2020.3.89–95
9. McKenna K., Rahman K., Parham K. Otoconia degeneration as a consequence of primary hyperparathyroidism. Med Hypotheses. 2020 Nov; 144:109982. doi: 10.1016/j.mehy.2020.109982. Epub 2020 Jun 7. PMID: 32531542.
Review
For citations:
Bedenko A.S. Benign paroxysmal positional vertigo: case developed with hyperparathyreoidism and vitamin D deficiency. Neurology and psychiatry (1). 2024;(2):50-52. (In Russ.) https://doi.org/10.33667/2078-5631-2024-2-50-52