Evaluation of the effectiveness of immunomodulatory therapy in the treatment of traumatic lesions of the oral mucosa in orthodontic patients
https://doi.org/10.33667/2078-5631-2023-20-35-37
Abstract
Relevance. The problem of traumatization of the oral mucosa with fixed orthodontic structures, especially at the initial stage of treatment, is one of the most urgent in orthodontics. Prolonged use of such structures often leads to adverse reactions from the oral mucosa in the form of chronic mechanical injury, burning, soreness, etc. The effectiveness of the use of alginate plates of the drug «Superlimf» as a correction of side effects from non-removable orthodontic equipment has been studied.
Objective. To study the effectiveness of the use of the domestic cytokine preparation «Superlimf» in the form of alginate plates in the treatment of traumatic lesions of the oral mucosa that occur in patients at the stages of orthodontic treatment with fixed equipment.
Materials and methods. The study included 35 people aged 18 to 25 years, of which 17 people used alginate plates «Superlimf» and 18 people – the control group – used orthodontic wax to protect the mucosa from injury.
Results. The use of alginate plates «Superlimf» showed a reduction in the duration of the inflammatory process, a significant reduction in painful manifestations and swelling.
Conclusion. The data obtained indicate the effectiveness of the drug «Superlimf» and allow us to recommend it for use in dental clinical practice.
About the Authors
S. V. Proskokova
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Proskokova Svetlana Vladimirovna - Doctor of Medical Sciences, Professor, Head of the Department of Orthopedic Dentistry
V. A. Voronetskaya
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Voronetskaya Viktoriya Aleksandrovna - Assistant of the Department of Orthopedic Dentistry
A. M. Enikeev
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Enikeev Amir Maratovich - Assistant of the Department of Orthopedic Dentistry
D. N. Kutuzov
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Kutuzov Dmitry Nikolaevich - Candidate of Medical Sciences, Associate Professor of the Department of Orthopedic Dentistry
A. E. Pirogov
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Pirogov Andrey Evgenievich - Assistant of the Department of Orthopedic Dentistry
K. M. Bogdanova
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Bogdanova Karina Mikhailovna - Assistant of the Department of Orthopedic Dentistry
References
1. Shadi TED. Characteristics of the frequency and prevalence of complications arising in the process of orthodontic treatment with fixed devices in the city of Voronezh. Diss. Candidate of Medical Sciences. Voronezh, 2012.
2. Bellamine M, Ousehal L, Kissa J. Orthodontic treatment and gingival hyperplasia: a case report. Odontostomatol Trop 2012;35(138):31–41. Bellamine M, Ousehal L, Kissa J. Orthodontic treatment and gingival hyperplasia: a case report. Odontostomatol Trop 2012;35(138):31–41.
3. Dr Cross D, Glasgow University, Glasgow, Lanarkshire, UK. Necrotizing ulcerative gingivitis and the orthodonti cpatient: a case series. J Orthod 2013;40(1):77–80.
4. S.N. Gontarev, Yu.A. Chernysheva, I.E. Fedorova, I.S. Gontareva. Inflammatory diseases of the oral mucosa when using removable and non-removable orthodontic equipment. SCIENTIFIC BULLETIN. Medicine series. Pharmacy. 2013. № 11 (154).
5. Vavilova, T.P. Prevention of dental diseases in the treatment of modern orthodontic devices / T.P. Vavilova, M.V. Korzhukova. M., 1997. – pp. 7–28.
6. Averyanov S.V., Khairzamanova K.A., Kazakova M.A. Prevalence of traumatic injuries of the oral mucosa during orthodontic treatment. Pediatric dentistry and prevention. 2017;2(61):76–78.
7. Iordanishvili A.K. Traumatic injuries of the oral mucosa during orthodontic treatment: a methodology for evaluating the effectiveness of using domestic remedies for local treatment. Russian dentistry. 2019;12(4):3–8. https://doi.org/10.17116/rosstomat2019120419.
8. Pustovalova R.A., Petrova M.B. Immunocorrecting effect of the drug «Superlimf» on wound healing. – Morphology. – 2008; 2: 110b eLibrary ID: 11642027.
9. Kovalchuk L.V., Gankovskaya L.V., Yarygin N.V., Yarema V.I., Doctors A.A., Dolgina E.N., Chadaev A.P., Alikhanov H.A. «Superlimf» in the complex treatment of complicated wound process. – Immunopathology, allergology, infectology. – 2005; 2: 33–43 eLibrary ID: 21144137.
10. Kovalchuk L.V., Ganskovskaya L.V., Kharaeva Z.F. Mechanism of action of the drug «Superlimf» on neutrophils of human peripheral blood. Immunology 2003; 2: 86-898.
Review
For citations:
Proskokova S.V., Voronetskaya V.A., Enikeev A.M., Kutuzov D.N., Pirogov A.E., Bogdanova K.M. Evaluation of the effectiveness of immunomodulatory therapy in the treatment of traumatic lesions of the oral mucosa in orthodontic patients. Medical alphabet. 2023;(20):35-37. (In Russ.) https://doi.org/10.33667/2078-5631-2023-20-35-37
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