Gynecomastia associated with methotrexate therapy for psoriatic arthritis
https://doi.org/10.33667/2078-5631-2022-29-53-56
Abstract
Methotrexate is widely used for treatment rheumatic diseases, including psoriatic arthritis. Adverse reactions could develop during methotrexate therapy, the most common of which are skin lesions, liver dysfunction, diarrhea, nausea, etc. Gynecomastia is a rare complication of low-dose methotrexate therapy. The mechanism of its development is not fully understood. We present a case report of the development of gynecomastia in a patient with psoriatic arthritis during treatment with methotrexate.
About the Authors
M. A. Borisova
A.S. Loginov Moscow Clinical Scientific Center
Russian Federation
Russian Federation
Borisova Maria A. - PhD Med, senior scientist.
Moscow
G. V. Lukina
A.S. Loginov Moscow Clinical Scientific Center; V.A. Nasonova Research Institute of Rheumatology
Russian Federation
Russian Federation
Lukina Galina V. - DM Sci (habil.), professor, head of Moscow City Rheumatology Centre A.S. Loginov MCSC, leading scientist at Laboratory of Evolution of Rheumatoid Arthritis.
Moscow
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Review
For citations:
Borisova M.A., Lukina G.V. Gynecomastia associated with methotrexate therapy for psoriatic arthritis. Medical alphabet. 2022;(29):53-56. (In Russ.) https://doi.org/10.33667/2078-5631-2022-29-53-56
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