Лекарственная терапия второй и последующих линий при раке желудка. Шаг вперед после долгих лет застоя?
Аннотация
В данной статье суммированы последние данные, касающиеся лекарственной терапии второй и последующих линий пациентов с метастатическим раком желудка. Рассматриваются различные варианты классической химиотерапии, а также таргетная терапия, в частности, анти-PD моноклональные антитела и рамуцирумаб, достоверно увеличивающие продолжительность жизни пациентов. Применение прогностических моделей, основанных на факторах риска, позволяет отбирать пациентов с наибольшим выигрышем от проведения терапии второй линии.
Ключевые слова
Об авторах
А. А. Трякин
ФГБУ «Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина» Минздрава России
Россия
Россия
М. Ю. Федянин
ФГБУ «Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина» Минздрава России
Россия
Россия
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Рецензия
Для цитирования:
Трякин А.А., Федянин М.Ю. Лекарственная терапия второй и последующих линий при раке желудка. Шаг вперед после долгих лет застоя? Медицинский алфавит. 2017;2(25):6-11.
For citation:
Tryakin A.A., Fedyanin M.U. Second and further lines of the therapy in metastatic gastric carcinoma. Step forward after stagnation years? Medical alphabet. 2017;2(25):6-11. (In Russ.)
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