Difficulties in differential diagnosis of inflammatory bowel diseases in patient with overlapping autoimmune hepatitis and primary sclerosing cholangitis
https://doi.org/10.33667/2078-5631-2021-6-26-30
Abstract
The article presents a clinical case of cross-syndrome of autoimmune hepatitis type 1 with primary sclerosing cholangitis. The main symptoms, laboratory and instrumental criteria of these diseases are discussed. Detection of specific antibodies is necessary for an accurate diagnosis. Interpretation of changes in the colon obtained by stepwise biopsy requires special attention. The described morphological picture does not allow to make an accurate diagnosis, it can be regarded as initial manifestations of Crohn's disease, microscopic or eosinophilic colitis, signs of worm-parasitic invasion. An example of a differential diagnostic search in such a situation is discussed.
Keywords
Supporting agencies: The work was prepared within the framework of a grant from the President of the Russian Federation for state support of leading scientific schools (ext. No. NSh-2558.2020.7) (acc. No. 075–15–2020–036 of March 17, 2020) ‘Development of health-preserving technology for a comorbid gastroenterological patient based on adherence control’.
About the Authors
T. S. Krolevets
Omsk State Medical University
Russian Federation
Russian Federation
Krolevets Tatyana S., PhD Med, associate prof. at Dept of Faculty Therapy and Gastroenterology
Omsk
M. A. Livzan
Omsk State Medical University
Russian Federation
Russian Federation
Livzan Maria A., DM Sci, prof., head of Dept of Faculty Therapy and Gastroenterology, rector
Omsk
M. I. Plinder
Omsk State Medical University
Russian Federation
Russian Federation
Plinder Maria I., clinical resident at Dept of Faculty Therapy and Gastroenterology
Omsk
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For citations:
Krolevets T.S., Livzan M.A., Plinder M.I. Difficulties in differential diagnosis of inflammatory bowel diseases in patient with overlapping autoimmune hepatitis and primary sclerosing cholangitis. Medical alphabet. 2021;1(6):26-30. (In Russ.) https://doi.org/10.33667/2078-5631-2021-6-26-30
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