Роль фармако- и микронутриентов в нутритивно-метаболической терапии COVID-19 и других вирусных инфекций

Недостаточность питания является неблагоприятным фоном для течения и исхода вирусных заболеваний, включая COVID-19. В соответствии с международными рекомендациями своевременная коррекция нутритивного статуса с помощью перорального, зондового энтерального и парентерального питания является необходимым и обязательным методом сопроводительной терапии COVID-19. Выполнен аналитический обзор результатов исследований клинического применения фармаконутриентов (глутамин; витамины А, С, D и Е; цинк, селен) с целью профилактики и лечения вирусных инфекций, включая COVID-19. В соответствии с данными клинических исследований, выполненных в 2019–2020 годах, применение глутамина и антиоксидантных микронутриентов в составе нутритивно-метаболической терапии позволяет снизить выраженность клинических симптомов и ускорить процесс восстановление пациентов с новой коронавирусной инфекцией COVID-19 и другими вирусными заболеваниями. С практической точки зрения, единственными источниками глутамина для энтерального введения, зарегистрированными в РФ, являются Глутамин Плюс для перорального энтерального питания и Интестамин для зондового энтерального введения, Дипептвен 20% – для парентерального введения. Применение фармаконутритивной терапии, в частности энтерального глутамина как компонента клинического питания у пациентов с вирусными инфекциями и нутритивной недостаточностью или риском ее развития, способствует улучшению клинических результатов, снижению тяжести течения заболевания и ускорению процесса реабилиитации.

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