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Роль фармако- и микронутриентов в нутритивно-метаболической терапии COVID-19 и других вирусных инфекций

https://doi.org/10.33667/2078-5631-2021-4-56-63

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Аннотация

Недостаточность питания является неблагоприятным фоном для течения и исхода вирусных заболеваний, включая COVID-19. В соответствии с международными рекомендациями своевременная коррекция нутритивного статуса с помощью перорального, зондового энтерального и парентерального питания является необходимым и обязательным методом сопроводительной терапии COVID-19. Выполнен аналитический обзор результатов исследований клинического применения фармаконутриентов (глутамин; витамины А, С, D и Е; цинк, селен) с целью профилактики и лечения вирусных инфекций, включая COVID-19. В соответствии с данными клинических исследований, выполненных в 2019–2020 годах, применение глутамина и антиоксидантных микронутриентов в составе нутритивно-метаболической терапии позволяет снизить выраженность клинических симптомов и ускорить процесс восстановление пациентов с новой коронавирусной инфекцией COVID-19 и другими вирусными заболеваниями. С практической точки зрения, единственными источниками глутамина для энтерального введения, зарегистрированными в РФ, являются Глутамин Плюс для перорального энтерального питания и Интестамин для зондового энтерального введения, Дипептвен 20% – для парентерального введения. Применение фармаконутритивной терапии, в частности энтерального глутамина как компонента клинического питания у пациентов с вирусными инфекциями и нутритивной недостаточностью или риском ее развития, способствует улучшению клинических результатов, снижению тяжести течения заболевания и ускорению процесса реабилиитации.

Об авторах

А. В. Дмитриев
Ассоциация «Северо-Западная ассоциация парентерального и энтерального питания»
Россия

 Дмитриев Александр Владимирович 

Санкт-Петербург



И. А. Мачулина
ГБУЗ «Городская клиническая больница № 70 имени Е.О. Мухина Департамента здравоохранения города Москвы»
Россия

 Мачулина Ирина Александровна 

Москва



А. Е. Шестопалов
ФГБОУ ДПО «Российская медицинская академия непрерывного последипломного образования» Минздрава России; 3ФГБУ «Главный военный клинический госпиталь имени академика Н.Н. Бурденко» Минобороны России
Россия

 Шестопалов Александр Ефимович 

Москва



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Для цитирования:


Дмитриев А.В., Мачулина И.А., Шестопалов А.Е. Роль фармако- и микронутриентов в нутритивно-метаболической терапии COVID-19 и других вирусных инфекций. Медицинский алфавит. 2021;(4):56-63. https://doi.org/10.33667/2078-5631-2021-4-56-63

For citation:


Dmitriev A.V., Machulina I.A., Shestopalov A.E. Role of pharmaco- and micronutrients in nutritional metabolic therapy of COVID-19 and other viral infections. Medical alphabet. 2021;(4):56-63. (In Russ.) https://doi.org/10.33667/2078-5631-2021-4-56-63

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ISSN 2078-5631 (Print)