Obesity and thrombophilia as double threat of gestational complications
https://doi.org/10.33667/2078-5631-2020-26-57-61
Abstract
Purpose of the study. A systematic analysis of the data available in the modern literature on the pathogenetic relationships of obesity and thrombophilia, the search for markers and predictors of obstetric and thrombotic complications during gestation. Material and methods. The review includes data from domestic and foreign articles found in PubMed, CyberLeninka and еLibrary on this topic, published over the past 5–10 years. Results. The possible mechanisms and pathogenetic relationship of the pro-inflammatory, prothrombotic and endocrine statuses observed in obese women in the development of obstetric and thrombotic complications are clearly presented. Conclusion. Despite a significant amount of work devoted to the study of risk factors and pathogenetic mechanisms of the development of thromboembolic complications in obese women, the problem of identifying the causes and methods for correcting disorders has not been completely resolved and requires further study. At the same time, the annually increasing percentage of women with obesity of reproductive age poses new challenges for improving methods of pregravid preparation and for the effective prevention of thrombohemorrhagic complications during pregnancy, childbirth and the postpartum period.
About the Authors
M. M. Mukhtarova
Dagestan State Medical University
Russian Federation
Makhachkala
Russian Federation
Makhachkala
Z. A. Аbusueva
Dagestan State Medical University
Russian Federation
Makhachkala
Russian Federation
Makhachkala
T. Kh. Hashaeva
Dagestan State Medical University
Russian Federation
Makhachkala
Russian Federation
Makhachkala
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Review
For citations:
Mukhtarova M.M., Аbusueva Z.A., Hashaeva T.Kh. Obesity and thrombophilia as double threat of gestational complications. Medical alphabet. 2020;(26):57-61. (In Russ.) https://doi.org/10.33667/2078-5631-2020-26-57-61
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