Лекарственные средства, прием которых ассоциирован с развитием лекарственно-индуцированной (медикаментозной) депрессии
https://doi.org/10.33667/2078-5631-2020-11-36-45
Аннотация
Более 60 % всех депрессивных синдромов составляет реактивная депрессия, возникающая в ответ на внутренние и внешние воз- действия. Одним из вариантов реактивной депрессии является ле- карственно-индуцированная (медикаментозная) или ятрогенная депрессия, которая является возможным побочным эффектом ряда лекарственных средств (ЛС). Депрессогенный эффект описывают как у психотропных, так и у соматотропных ЛС. Де- прессии, возникающие при применении психотропных средств, чаще всего связаны с длительностью приема и большими дозами препарата. В ряду соматотропных препаратов, обладающих депрессогенным эффектом, чаще всего упоминаются некоторые антигипертензивные, антиаритмические, гиполипидемические ЛС, антибиотики, гормоны, противопаркинсонические, противоопухолевые ЛС. Лекарственно-индуцированные депрессии – одна из наиболее спорных проблем, в данной статье представлена систематизация имеющихся литературных данных о депрессии, ассоциированной с приемом различных ЛС.
Об авторах
О. Д. ОстроумоваРоссия
д. м. н., проф., зав. кафедрой терапии и полиморбидной патологии; проф. кафедры клинической фармакологии и пропедевтики внутренних болезней
г. Москва
С. В. Батюкина
Россия
ординатор II года кафедры терапии и полиморбидной патологии
г. Москва
Е. Ю. Эбзеева
Россия
к. м. н., доцент, доцент кафедры терапии и полиморбидной патологии
г. Москва
Н. А. Шаталова
Россия
ординатор II года кафедры терапии и полиморбидной патологии
г. Москва
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Рецензия
Для цитирования:
Остроумова О.Д., Батюкина С.В., Эбзеева Е.Ю., Шаталова Н.А. Лекарственные средства, прием которых ассоциирован с развитием лекарственно-индуцированной (медикаментозной) депрессии. Медицинский алфавит. 2020;1(11):36-45. https://doi.org/10.33667/2078-5631-2020-11-36-45
For citation:
Ostroumova O.D., Batyukina C.V., Ebzeeva E.Yu., Shatalova N.A. Medications associated with development of drug-induced depression. Medical alphabet. 2020;1(11):36-45. (In Russ.) https://doi.org/10.33667/2078-5631-2020-11-36-45