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Лекарственные средства, прием которых ассоциирован с развитием лекарственно-индуцированной (медикаментозной) депрессии

https://doi.org/10.33667/2078-5631-2020-11-36-45

Полный текст:

Аннотация

Более 60 % всех депрессивных синдромов составляет реактивная депрессия, возникающая в ответ на внутренние и внешние воз- действия. Одним из вариантов реактивной депрессии является ле- карственно-индуцированная (медикаментозная) или ятрогенная депрессия, которая является возможным побочным эффектом ряда лекарственных средств (ЛС). Депрессогенный эффект описывают как у психотропных, так и у соматотропных ЛС. Де- прессии, возникающие при применении психотропных средств, чаще всего связаны с длительностью приема и большими дозами препарата. В ряду соматотропных препаратов, обладающих депрессогенным эффектом, чаще всего упоминаются некоторые антигипертензивные, антиаритмические, гиполипидемические ЛС, антибиотики, гормоны, противопаркинсонические, противоопухолевые ЛС. Лекарственно-индуцированные депрессии – одна из наиболее спорных проблем, в данной статье представлена систематизация имеющихся литературных данных о депрессии, ассоциированной с приемом различных ЛС.

Об авторах

О. Д. Остроумова
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России; ФГАОУ ВО «Первый Московский государственный медицинский университет имени И. М. Сеченова (Сеченовский университет)» Минздрава России
Россия

д. м. н., проф., зав. кафедрой терапии и полиморбидной патологии; проф. кафедры клинической фармакологии и пропедевтики внутренних болезней

г. Москва



С. В. Батюкина
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России
Россия

ординатор II года кафедры терапии и полиморбидной патологии

г. Москва



Е. Ю. Эбзеева
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России
Россия

к. м. н., доцент, доцент кафедры терапии и полиморбидной патологии

г. Москва



Н. А. Шаталова
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России
Россия

ординатор II года кафедры терапии и полиморбидной патологии

г. Москва



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Для цитирования:


Остроумова О.Д., Батюкина С.В., Эбзеева Е.Ю., Шаталова Н.А. Лекарственные средства, прием которых ассоциирован с развитием лекарственно-индуцированной (медикаментозной) депрессии. Медицинский алфавит. 2020;1(11):36-45. https://doi.org/10.33667/2078-5631-2020-11-36-45

For citation:


Ostroumova O.D., Batyukina C.V., Ebzeeva E.Yu., Shatalova N.A. Medications associated with development of drug-induced depression. Medical alphabet. 2020;1(11):36-45. (In Russ.) https://doi.org/10.33667/2078-5631-2020-11-36-45

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