Clinical efficacy of complex therapy in patients with chronic pancreatitis and atherosclerosis using ursodeoxycholic acid and high doses of substitute therapy with pancreatic enzymes
https://doi.org/10.33667/2078-5631-2019-2-20(395)-51-53
Abstract
The results are presented and the efficacy of prescribing ursodeoxycholic acid and high doses of replacement therapy with pancreatic enzymes for clinical and laboratory indicators in patients with chronic pancreatitis and atherosclerosis is analyzed. The positive effect of the drug UDCA at a dose of 15 mg/kg of body weight for 3 months and high doses of substitution therapy with Pangrol 25 000, 2 capsules 3 times per day for symptoms of diseases, lipid profile, 13C-amylase and 13C-mixed triglyceride breathing tests in these patients.
About the Authors
E. S. Sirchak
Uzhgorod National University
Ukraine
Uzhgorod
Ukraine
Uzhgorod
S. M. Opalenyk
Uzhgorod National University
Ukraine
Uzhgorod
Ukraine
Uzhgorod
References
1. Бабинец Л. С. Плейотропные свойства омега-3 полиненасыщенных жирных кислот в комплексном лечении пациентов с коморбидностю хронического панкреатита и стабильной ишемической болезни сердца / Л. С. Бабинец, Н. А. Мельник // Вестник клуба панкреатологов. — 2018. — С. 22–27.
2. Пасиешвили Л. Н. Ассоциация метаболических и генетических маркеров риска развития остеопенических состояний при сочетании хронического панкреатита и гипертонической болезни / Л. Н. Пасиешвили, Т. И. Вьюн, А. А. Лазуткина // Достижения клинической и экспериментальной медицины. — 2018. — № 2. — С. 81–85.
3. Аjaikumar B. Kunnumakkara. Chronic diseases, inflammation, and spices: how are they linked? / Аjaikumar B. Kunnumakkara, Вethsebie L. Sailo, Kishore Banik, Choudhary Harsha, Sahdeo Prasad et el. // Journal of Translational Medicin. — 2018. — Р. 1–25.
4. Dominguez-Muñoz. Diagnosis and treatment of pancreatic exocrine insufficiency / Dominguez-Muñoz, J. Enrique // Current Opinion in Gastroenterology. — September 2018. — Vol. 34. — Issue 5. — Р. 349–354.
5. Daniel de la Iglesia-Garcia. Increased Risk of Mortality Associated With Pancreatic Exocrine Insufficiency in Patients With Chronic Pancreatitis / Daniel de la Iglesia-Garcia, Nicolau Vallejo-Senra, Julio Iglesias-Garcia, Andrea López-López, Laura Nieto, J. Enrique Domínguez-Muñoz // Journal of Clinical Gastroenterology. — September 2018. — Vol. 52. — Issue 8. — Р. 63–72.
Review
For citations:
Sirchak E.S., Opalenyk S.M. Clinical efficacy of complex therapy in patients with chronic pancreatitis and atherosclerosis using ursodeoxycholic acid and high doses of substitute therapy with pancreatic enzymes. Medical alphabet. 2019;3(20):51-53. (In Russ.) https://doi.org/10.33667/2078-5631-2019-2-20(395)-51-53
Views:
930
Email this article 