Ozone therapy in complex treatment of leukoplakia of oral mucosa
Abstract
The study included patients with a form of verrucous leukoplakia of the oral mucosa, the treatment of which was carried out by traditional scheme (cryosurgery and topical anti-inflammatory treatment - 1st group) and with postoperative ozonated olive oil solution with a known peroxide value (second group). To assess the effectiveness of the chosen postoperative wound method using a comparative analysis of the results of the patients oral fluid with the 1st and 2nd groups. As a criterion used indicator of the activity of superoxide dismutase (SOD) oral fluid. We get more significant increase in the activity of SOD oral liquid in the postoperative period using ozonated oil than adaptive zoom cryoablation. Use during the postoperative period in the complex treatment of the ozonized solution of olive oil resulted in lower levels of oxidative stress in the saliva due to the persistent and long-term increase of activity of salivary SOD that accelerated repair processes, improved during the wound healing process, reduce the life of the oral mucosa healing (confirmed by morphological studies) compared to conventional treatments.
About the Authors
K. V. Zyablitskaya
Altai State Medical University
Russian Federation
Russian Federation
E. N. Vorobyova
Altai State Medical University
Russian Federation
Russian Federation
S. I. Tokmakova
Altai State Medical University
Russian Federation
Russian Federation
E. A. Sharlaeva
Altai State University
Russian Federation
Russian Federation
G. G. Sokolova
Altai State University
Russian Federation
Russian Federation
I. A. Batanina
Clinical Hospital at the station Barnaul of Russian Railways
Russian Federation
Russian Federation
O. V. Bondarenko
Altai State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Zyablitskaya K.V., Vorobyova E.N., Tokmakova S.I., Sharlaeva E.A., Sokolova G.G., Batanina I.A., Bondarenko O.V. Ozone therapy in complex treatment of leukoplakia of oral mucosa. Medical alphabet. 2018;1(2):11-15. (In Russ.)
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