Summary electroencephalography: the concept of multiple generation mechanisms
https://doi.org/10.33667/2078-5631-2025-24-60-68
Abstract
The concept of formation of the summary electroencephalogram is proposed, based on the hypothesis of the existence of three different, but interconnected mechanisms of bioelectrical activity generation: dendritic integration processes, processes of change in the level of constant potential, impulse activity of cortical neurons. The interaction of sources of different nature underlies the activity recorded on the summary EEG. With the dominance of the thalamocortical system, rhythmic activity is recorded, the frequency of which depends on the functional state of the central nervous system. Discharge forms of activity on the EEG reflect the hypersynchronous impulse activity of a large pool of cortical neurons. The basis of the slow-wave activity of the delta range are dysmetabolic processes, on the one hand, suppressing the thalamocortical mechanism, on the other, causing pronounced changes in the constant potential. The proposed concept is aimed not only at explaining the diversity of EEG phenomenology, but also opens up opportunities for finding new methods of EEG analysis based on an understanding of physiological mechanisms.
About the Authors
M. V. Aleksandrov
Federal State Budgetary Institution «Almazov National Medical Research Centre» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Doctor of Medical Sciences, Professor, Head of the Department ofClinical Neurophysiology
St. Petersburg
E. L. Masherov
Federal State Autonomous Institutions «National Medical Research Center of Neurosurgery named after Academician N. N. Burdenko» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Candidate of Technical Sciences, Senior Researcher, Clinical Neurophysiology Laboratory
Moscow
L. B. Ivanov
State Budgetary Institution of Science «Children’s City Clinical Hospital No. 9 named after G.N. Speransky of the Moscow Department of Health»
Russian Federation
Russian Federation
Candidate of Medical Sciences, Head of the Diagnostic Department
Moscow
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For citations:
Aleksandrov M.V., Masherov E.L., Ivanov L.B. Summary electroencephalography: the concept of multiple generation mechanisms. Medical alphabet. 2025;(24):60-68. (In Russ.) https://doi.org/10.33667/2078-5631-2025-24-60-68
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