Evaluation of the effectiveness and safety of a complex herbal remedy for the prevention of inflammatory diseases of the oral cavity

   The article presents the results of testing the herbal-based mouthwash «Art-Dentale Expert» for compliance with regulatory requirements, including safety analysis, packaging, and labeling.

   The study aimed to evaluate the mouthwash’s safety and consumer satisfaction through a questionnaire survey.

   Findings. The «Art-Dentale Expert» mouthwash complies with the standards TRCU 009/2011 «On the Safety of Perfumery and Cosmetic Products». A survey of 70 patients with mild chronic generalized periodontitis showed significant reductions in gum bleeding and good tolerability of the product. However, 34 % of respondents expressed dissatisfaction with the need to dilute solution the mouthwash before use.

   Conclusions. The product meets various regulatory standards, including requirements for appearance, pH, toxic element content, microbial safety, packaging, and labeling. It can be recommended for use in the comprehensive treatment of chronic generalized periodontitis. Positive attributes noted by respondents included taste (87.14 %), smell (63.16 %), a pleasant feeling after use (92.86 %), gum recovery (90 %), reduction in gum bleeding (100 %), tolerability (97.14 %), and rapid therapeutic effects (72.86 %). No adverse effects were reported, but the dilution requirement was a notable drawback for some users.

1. Mkhoyan G.R., Razumova S.N., Volkov A.G., et al. «Influence of removal of dental deposits using low-frequency ultrasound and ozonated contact medium on the gingival sulcus microbiota in young individuals with chronic catarrhal gingivitis» / Medical Alphabet. 2021;(24):98–101. DOI: 10.33667/2078-5631-2021-24-98-101. EDN: ZAFVHM.

2. Tabet M.A.K., Razumova S.N., Brago A.S., et al. «Conducting professional hygiene for patients using various methods : A literature review. Medical Alphabet» 2022; (7): 15–19. DOI: 10.33667/2078-5631-2022-7-15-19. EDN: YCIIXN.

3. Panov S.N., Mikhailova E.S., Koroleva I.V., et al. «Clinical evaluation of periodontal tissue condition during the complex treatment of patients with chronic generalized periodontitis using a herbal mouthwash» Russian Dental Journal. 2023; 27(5): 431–441. DOI: 10.17816/dent568294. EDN: GRCKMG.

4. Panov S.N., Marakhova A.I., Zhilkina V.Y., et al. «Oral care product with antimicrobial action»: No. 2018109419; filed March 16, 2018; published July 12, 2019. Patent No. 2694415 C1 Russian Federation, IPC A61K 36/185, A61K 36/53, A61K 36/61. – EDN: PLUCBS.

5. Marakhova A.I., Sachivkina N.P., Panov S.N., Razumova S.N. «Development of a comprehensive herbal remedy for the prevention of inflammatory oral diseases» / Medical Bulletin of Bashkortostan. 2022; (5)101. URL: https://cyberleninka.ru/article/n/razrabotka-kompleksnogo-rastitelnogo-sredstva-dlya-profilaktiki-vospalitelnyh-zabolevaniy-polosti-rta (Accessed May 4, 2024).

6. ADA recommendations on the effectiveness and safety of mouthwashes // Oral Hygiene. 2007 (special supplement to Access journal). 15 p.

7. Customs Union Technical Regulation «On the Safety of Perfumery and Cosmetic Products» (TR CU 009/2011).

8. Bolsunovskaya Yu.R., Arkhipov V.V. «Results of Surveying Cardiologists and Clinical Pharmacologists on the Selection and the Efficacy and Safety Evaluation of Pharmacotherapy for Cardiovascular Diseases» Safety and Risk of Pharmacotherapy. 2022;10(4):411–419.