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Pustular psoriasis treated with IL-17a antibody secukinumab

https://doi.org/10.33667/2078-5631-2022-27-30-36

Abstract

 The article presents clinical cases of treatment of acute generalized pustular psoriasis (GPP) with the use of an interleukin IL-17A inhibitor, secukinumab, which showed a remarkable response with almost complete disappearance of pustules after the first injection. To the best of our knowledge, there are limited data in the literature on evaluating the effectiveness of therapy with genetically engineered drugs in the treatment of GPP. 

About the Authors

N. S. Rudneva
Tula Regional Clinical Dermatovenerologic Dispensary; Tula State University
Russian Federation

Rudneva Natalya S., PhD Med, chief physician1, associate professor at Dept
of Propaedeutics of Internal Diseases (Course of Dermatovenereology); chief
freelance specialist – dermatovenereologist, cosmetologist of the Ministry of Health of the Tula Region 

 Tula



E. V. Natarova
Tula Regional Clinical Dermatovenerologic Dispensary
Russian Federation

Natarova Ella V., deputy chief physician for medical work 

 Tula 



L. S. Kruglova
Central State Medical Academy of the Administrative Department of the President of Russian Federation
Russian Federation

Kruglova Larisa S., DM Sci (habil.), professor, head of Dept of Dermatovenereology and Cosmetology 

Moscow 



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Review

For citations:


Rudneva N.S., Natarova E.V., Kruglova L.S. Pustular psoriasis treated with IL-17a antibody secukinumab. Medical alphabet. 2022;1(27):30-36. (In Russ.) https://doi.org/10.33667/2078-5631-2022-27-30-36

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ISSN 2078-5631 (Print)
ISSN 2949-2807 (Online)